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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (758) clinical trials

Studying Lymph Nodes in Patients With Stage II Colon Cancer

OBJECTIVES Determine whether the immunohistochemical and molecular presence of micrometastases in 12 lymph nodes removed during en-bloc resection in patients with stage II colon cancer correlates with 3-year disease-free survival. Evaluate the prognostic significance of molecular markers detected in the primary tumor and develop a microarray-based gene signature for stage ...

Phase N/A

A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer

Artemisinins are a family of sesquiterpene trioxane anti-malarial agents derived from Sweet Wormwood (Artemisia annua L), a plant that has been used in traditional Chinese medicine for centuries. Artesunate is a derivative of artemisinin that is converted into its active metabolite dihydroartemisinin (DHA). Artesunate is a widely used antimalarial with ...


Multi Parametric Test Predicting the Risk of Colorectal Neoplasia Recurrence

In this project, 200 individuals (aged 18 - 75 years) with removed colorectal polyps larger than 10 mm during colonoscopy performed based on all indication (including symptoms and screening procedures) will be included. All procedures will be done with high quality endoscopes (high definition, HD). In all polyps, the advanced ...

Phase N/A

Aspirin in Colorectal Cancer Liver Metastases

The ASAC trial is a Scandinavian, multi-center, double-blinded, randomized, placebo-controlled study to determine whether adjuvant treatment with low-dose acetylsalicylic acid (ASA) can improve disease free survival in patients treated with resection for colorectal cancer liver metastases (CRCLM). Several studies have shown beneficial effect of ASA on primary prevention of CRC ...


Physical Activity in Patients With Metastatic Colorectal Cancer Who Receive Palliative First-line Chemotherapy

While safety and feasibility as well as some improvements in fitness, fatigue and certain aspects of quality of life have been shown for physical activity in cancer patients during treatment, none of the pre-requisites above (i-iv) is fulfilled in the setting of patients with advanced colon cancer. However, evidence, primarily ...


U01 CRC Project for Vietnamese Americans

Colorectal cancer (CRC) is the second most commonly diagnosed cancer and the third highest cause of mortality in Vietnamese and Asian Americans. CRC incidence is rising rapidly in Vietnamese Americans, but they have among the lowest rates of CRC screening (14%) and are more likely to be diagnosed with advanced ...

Phase N/A

Tissue Procurement for Gastric Cancer Gastrointestinal Stromal Tumors (GIST) Esophageal Cancer Pancreas Cancer Hepatocellular Cancer Biliary Cancer Neuroendocrine Peritoneal Mesothelioma Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

The purpose of this study is to collect and store normal and malignant tissue from patients with gastric cancer, GIST, esophageal cancer, pancreas cancer, hepatocellular cancer, biliary cancer, neuroendocrine, peritoneal mesothelioma, anal cancer and colorectal cancer, an estimated 50 to 100 of each tumor type. To collect and store blood ...

Phase N/A

Observational Study to Evaluate the Use of Targeted Therapies in Metastatic Colorectal Cancer

The purpose of this study is to evaluate, in terms of overall survival, the benefit of monoclonal antibodies in the start time of the diagnosis of advanced disease or administer a deferred basis after progression to treatment with chemotherapy alone.

Phase N/A

Comparison of AMR and ADR Between Endocuff Vision-assisted and Conventional Colonoscopy: a Multicenter Randomized Trial

Rationale: Population screening programs for colorectal cancers (CRC) are increasingly adapted as a public health initiative with the primary goal to prevent CRC and CRC related deaths. [2-4] The ultimate benefit of CRC screening relies on the detection and resection of (pre-)malignant colon lesions, and for this colonoscopy is the ...

Phase N/A

CYCORE: Cyberinfrastructure for Comparative Effectiveness Research - Feasibility Trial

If you agree to take part in this study, you will complete physical fitness tests, questionnaires, and training sessions at 4 different time points: Before surgery, either during your clinic visit or by phone. This session will take about 75 minutes. About 1 week after you are discharged from the ...

Phase N/A