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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (15) clinical trials

Mechanistic and Molecular Study of the Process of Metastatic Dissemination in Colorectal Cancer

To confirm the role of the collective dissemination in the mechanisms of tumoral invasion of colorectal cancers

Phase N/A

Autohypnosis and Cancerology

Therapeutical hypnosis is proven to be an effective medical support to chemotherapy: it was shown that it can reduce the pain, anxiety, fatigue felt by the patient. Yet, hypnosis requires the presence of an hypnotherapist, which is why auto-hypnosis could be an efficient alternative to handle the side effects of ...

Phase N/A

METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin

Hypothesis: Most patients with mCRC harbor tumor that can be transformed into an immunogenic disease by oxaliplatin, and may thereby benefit from the addition of immune-modulating therapy to improve outcome of the current oxaliplatin-based standard-of-care. Primary objective: To determine progression-free survival (PFS), in terms of failure of treatment strategy, of ...


mFOLFOX6 Chemotherapy With Apatinib as Postoperative Treatment in Stage IIIB or IIIC Colorectal Cancer

This study will focus on postoperative patients of stage IIIB or stage IIIC colorectal cancer. These patients will start to accept chemotherapy in 3-4 weeks after operation, these patients were randomly divided into two groups, one group will accept adjuvant chemotherapy of mFOLFOX6; another group will use mFOLFOX6 combined with ...


Immunophenotyping of Metastases From Colorectal Cancer

There is extensive evidence for molecular heterogeneity in CRC. Studies have revealed that intra-tumour heterogeneity can be highly variable within primary tumours or between primary and metastatic sites (1). Moreover, tumour heterogeneity can be linked to targeted therapies in terms of acquired resistance mutations (2). In the era of precision ...

Phase N/A

Adenoma Detection Rate With Endocuff-Assisted Colonoscopy - an Italian Trial

In European countries, colorectal cancer (CRC) represents an important public health problem. It is widely held view that most carcinomas develop from an adenoma-carcinoma progression. It has been demonstrated that screening with fecal occult blood test (FOBT) significantly reduces mortality for CRC. Currently, population-based CRC screening programs using FOBT have ...

Phase N/A

Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS

The main objective is to determine if perioperative nutritional support with PeriOlimel N4-E, that reaches nutritional requirements of ERAS protocol for colorectal cancer surgery patients, can improve nutritional status so it decreases postoperative complications, hospital length of stay and costs, compared to conventional fluid therapy administration since patients receive oral ...


Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners

PRIMARY OBJECTIVES: I. To examine the feasibility and acceptability of couples' acceptance and commitment therapy (ACT) (C-ACT). II. To collect pilot data on the impact of C-ACT on patients' and partners' anxiety, depression, and quality of life. OUTLINE Patients and their partners attend 6 weekly ACT sessions over 60-75 minutes. ...

Phase N/A

Colorectal Neoplasia and Microbiota: Does Left Equal Right?

Many studies, including our own, have shown that colorectal cancer (CRC) is related to changes in the microbiome of the colon Certain bacterial phyla are more frequently presented in CRC Bacterial diversity is reduced in CRC Co-occurrence of bacterial phyla and exclusion are identified in CRC Besides bacteriome, viromes have ...

Phase N/A

Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy

Confocal Endomicroscopy procedure: eligible patients which consent to participate in the study will be submitted to endoscopic procedures under conscious or deep sedation. The patients will receive an intravenous injection of 2.5-5 mL of 10% sodium fluorescein at the beginning of the endoscopic procedure. The endoscope will target the area ...

Phase N/A