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Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (379) clinical trials

Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer

OBJECTIVES: Primary - Compare the disease-free survival rate in women with stage III breast cancer treated with adjuvant chemotherapy with vs without darbepoetin alfa. Secondary - Compare local recurrence and overall survival in patients receiving these regimens. - Compare toxicity of these regimens in these patients. - Compare quality of ...

Phase N/A

Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer

OBJECTIVES: - The primary objective is to determine the effectiveness the chemotherapy combination in improving the experience of those with advanced pancreatic cancer in - Pain control and other aspects of quality of life - Reduction of the tumor size or stabilization of tumor growth - Progression free survival - ...


Tolerance and Pharmacokinetics With Capecitabine 5 Out of 7 Days Regimen

Standard administration of capecitabine use a 14 days administration. Routine practice in several intitution leads to use a 5 out of 7 days regimen, with less toxicity. Purpose : to compare the pharmacokinetics of capecitabine, administered 5 days out of 7, as compared to the standard administration (14 days out ...


Respiratory Side Effects of Busulfan High Dose Chemotherapy in a Pediatric Population

Recently, several conditioning regimens did not include total body irradiation (TBI) anymore, especially in the case of young children due to cognitive sequelae and late effects on growth and height. Thus, such effective chemotherapy conditioning regimens were developed to avoid these complications. Busulfan is one of the major drugs used ...


Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

OBJECTIVES: - Determine the dose of daunorubicin hydrochloride that is equivalent to 30 mg/m² of doxorubicin hydrochloride in pediatric patients with acute lymphoblastic leukemia (ALL). - Determine whether it is possible to reduce therapy in pediatric patients with low-risk ALL and a PVA (prednisolone-vincristine-asparaginase) score of 3+4 without loss of ...

Phase N/A

S-1 and Irinotecan Combination Chemotherapy for Advanced Gastric Cancer

The primary goal of this phase II trial is to evaluate the response rate of combination chemotherapy with S-1 and Irinotecan in patients with advanced gastric cancer as a first-line therapy.


Intraperitoneal Hyperthermic Chemotherapy in Epithelial Ovarian Carcinoma

Phase II to study results and morbidity of intra peritoneal hyper-thermic chemotherapy as consolidation therapy in patients with FIGO stage IIIC epithelial ovarian carcinoma treated by surgery and a total of 6 cycles of platinum based chemotherapy. A second look operation is performed after treatment; during this second look secondary ...


Effect of Chemotherapy Administered Before Surgery on Breast Cancers Bone Marrow Cancer Cells and Circulating Cancer Cells

In this study, we propose that persistent disseminated tumor cells (DTC) present after chemotherapy represent a unique subpopulation of all DTC, are predictors of a poor response to chemotherapy, and correlate with poor clinical outcome. We hypothesize that chemotherapy-resistant DTC can be identified by their expression of a unique constellation ...

Phase N/A

Alemtuzumab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II Stage III or Stage IV T-Cell Non-Hodgkin's Lymphoma

OBJECTIVES: Primary - Establish the safety and dose-limiting toxicities of alemtuzumab in combination with cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (CHOP) chemotherapy in patients with newly diagnosed, stage II-IV aggressive peripheral T-cell non-Hodgkin's lymphoma. - Measure the pharmacokinetics of alemtuzumab using different subcutaneous doses and schedules to determine the dose ...


Chemotherapy and Bevacizumab in Treating Women With Invasive Breast Cancer

OBJECTIVES: Primary - Determine the feasibility and toxicity of dose-dense adjuvant chemotherapy and bevacizumab followed by single-agent bevacizumab in women with lymph-node positive, invasive breast cancer. Secondary - Estimate the 2-year and 5-year disease-free survival of patients treated with this regimen. - Describe the detection rate of circulating tumor cells ...

Phase N/A