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Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (210) clinical trials

This research study will look at how effective niraparib (a PARP inhibitor) is compared to placebo (a pill with no medicine in it, like a sugar pill) in maintenance therapy for women who have ovarian, fallopian tube or peritoneal cancer, and have responded (complete or partial response) to front-line platinum-based ...

Phase

You are being asked to take part in this study because you have been diagnosed with cervical cancer which is locally advanced and not suitable for surgery. The alternative to treatment on this trial is to receive standard cisplatin chemotherapy given at the same time as radiation. The purpose of ...

Phase

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT01366183?term=GOG+0273&rank=1

Phase N/A

What Factors Affect Breast Cancer Neoadjuvant Chemotherapy Efficacy?

In this single group longitudinal study, the investigators propose that functional images from magnetic resonance (MR) methods performed at baseline and after 6 cycles of neoadjuvant chemotherapy (NACT) are in agreement with histological findings from pre-treatment biopsy and post-treatment surgically excised tissue. MR methods will be performed at baseline (pre-treatment) ...

Phase N/A

IGFBP-2 Vaccine and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian Fallopian Tube or Primary Peritoneal Cancer Undergoing Surgery

PRIMARY OBJECTIVES: I. Determine whether the addition of an IGFBP-2 vaccine to neoadjuvant chemotherapy increases the rate of complete pathologic response (CR). SECONDARY OBJECTIVES: I. Determine whether the addition of an IGFBP-2 vaccine to neoadjuvant chemotherapy increases progression free survival at 12 months. II. Determine whether the addition of an ...

Phase

MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian Fallopian or Peritoneal Cancer

PRIMARY OBJECTIVES: I. Compare clinical efficacy of Arm A (MV-NIS therapy) and Arm B (standard cytotoxic chemotherapy), as measured by overall survival (OS). SECONDARY OBJECTIVES: I. Compare progression-free survival (PFS), overall survival at 12 months (OS12), progression-free survival at six months (PFS6), and objective response rate (ORR) between MV-NIS therapy ...

Phase

PG2 Treatment Among Stage II/III Breast Cancer Patients Receiving Adjuvant Chemotherapy

Adjuvant chemotherapy usually is recommended after surgery for breast cancer patients who are at significant risk for disseminated disease. Chemotherapy has been demonstrated to reduce the risk of breast cancer recurrence. Anthracycline-based regimens, including doxorubin or epilubicin, are the breast cancer adjuvant chemotherapy standards of care. Fatigue has also been ...

Phase

Assessment of the Immunogenicity of Peg-filgrastim Versus Neulasta as an Adjunct to Chemotherapy in Patients With Breast Cancer

The purpose of this study is to compare the immunogenicity of Peg-filgrastim versus Neulasta as an adjunct to chemotherapy in patients with breast cancer

Phase

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Chinese Breast Cancer Patients

The Olanzapine Regimen will be superior to the Standard Regimen, as measured by the proportion of patients with Complete Response in the 120 hours following AC chemotherapy.

Phase

Surgery and Chemotherapy With or Without Chemotherapy After Surgery in Treating Patients With Ovarian Fallopian Tube Uterine or Peritoneal Cancer

PRIMARY OBJECTIVES: I. To determine whether cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) followed by postoperative normothermic intraperitoneal (IP) chemotherapy is feasible and safe to administer, as measured by toxicities occurring during treatment or follow-up. SECONDARY OBJECTIVES: I. To determine quality of life (QoL) and compare the outcomes to a ...

Phase