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Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (70) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT01366183?term=GOG+0273&rank=1

Phase N/A

This is a multicenter, *open-label, Phase 2 study to look at how safe and effective niraparib (**a PARP inhibitor) is in women with advanced, relapsed, high-grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer. Patients must have already received at least 3 chemotherapy regimens (including, but not limited to ...


You are being asked to take part in this study because you have been diagnosed with cervical cancer which is locally advanced and not suitable for surgery. The alternative to treatment on this trial is to receive standard cisplatin chemotherapy given at the same time as radiation. The purpose of ...


This research study will look at how effective niraparib (a PARP inhibitor) is compared to placebo (a pill with no medicine in it, like a sugar pill) in maintenance therapy for women who have ovarian, fallopian tube or peritoneal cancer, and have responded (complete or partial response) to front-line platinum-based ...


Paclitaxel (Phyxol) and Cisplatin as First-line Chemotherapy for Metastatic Breast Cancer

Breast cancer is one of the leading causes of cancer death for women in Taiwan. We have recently demonstrated that combination of paclitaxel and cisplatin, at conventional doses, is highly effective in the treatment of breast cancer. However, the acute and cumulative toxicities of paclitaxel have been troublesome to a ...


Estrogen Priming to Increase the Efficacy of Adjuvant Chemotherapy in Operable Breast Cancer

Results from a recent clinical study (1) show that tamoxifen administered concurrently with chemotherapy reduces the efficacy of the latter in patients with estrogen and/or progesterone receptor positive breast cancer. Tamoxifen exerts its anti-tumour efficacy in breast cancer primarily by its anti-estrogenic effect on the breast tissue. Anti-estrogenic effects of ...


Neoadjuvant Chemotherapy Followed by Surgery Versus Concurrent Chemoradiation in Carcinoma of the Cervix

Cancer of the uterine cervix is a major health problem in the developing countries including India and is the commonest cancer amongst women in India with nearly 1,00000 new women diagnosed to have this cancer every year. It is also the main cause of cancer related mortality among women in ...


Olaparib or Cediranib Maleate and Olaparib Compared With Standard Platinum-Based Chemotherapy in Treating Patients With Recurrent Platinum-Sensitive Ovarian Fallopian Tube or Primary Peritoneal Cancer

PRIMARY OBJECTIVES: I. Assess the efficacy of either single agent olaparib or the combination of cediranib (cediranib maleate) and olaparib, as measured by progression free survival (PFS), as compared to standard platinum-based chemotherapy in the setting of recurrent platinum-sensitive ovarian, primary peritoneal or fallopian tube cancer. SECONDARY OBJECTIVES: I. Assess ...


Pembrolizumab in Combination With Chemotherapy in Frontline Ovarian Cancer

Treatment: If participant is found to be eligible to take part in this study and agrees, participant will have standard chemotherapy, participant's scheduled surgery, and then chemotherapy in combination with pembrolizumab. Neoadjuvant Treatment: Participant will receive standard chemotherapy treatment for three 21-day cycles, or possibly more cycles if the doctor ...