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HIV Clinical Trials

A listing of HIV medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (184) clinical trials

Liver Fibrosis in HIV-Infected Patients With Elevated Liver Enzymes on Antiretroviral Therapy

At present, there are no clear guidelines as to when antiretroviral therapy for human immunodeficiency virus (HIV) infection should be stopped in the setting of elevated liver enzymes. In large part, this is due to a limited understanding of the natural history of antiretroviral-related hepatotoxicity. Although several antiretrovirals have been ...

Phase N/A

Viral Load Determination and Biomarkers of High Risk Human Papillomavirus (HPV) - Types in HIV-positive Men

Compared to the general population the incidence of anal intraepithelial neoplasia (AIN) and anal carcinoma (AC) amongst men who have sex with men (MSM) is extremely high (above 70/100,000). While many opportunistic infections have declined since the introduction of highly active antiretroviral therapy (HAART), the incidence of AC has not ...

Phase N/A

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant Women.

The following antiretroviral drugs are followed by the Antiretroviral Pregnancy Registry (APR: Registry) to detect any major teratogenic effect when administered to pregnant women: abacavir (ZIAGEN, ABC), abacavir/lamivudine combination (EPZICOM, EPZ), abacavir/lamivudine/zidovudine combination (TRIZIVIR, TZV), abacavir/dolutegravir/lamivudine combination (TRIUMEQ, TRI), adefovir dipivoxil (HEPSERA, ADV), amprenavir (AGENERASE, APV), atazanavir (REYATAZ, ATV), atazanavir/cobicistat ...

Phase N/A

A Long-term Follow-up of the HIV-NAT Cohort

Primary Objective: To collect and evaluate long-term clinical outcomes of HIV infected participants previously enrolled in HIV-NAT trials. Secondary Objective: To Assess: Long-term consequences of initiation of antiretroviral as predicted by baseline CD4 cell count and/or baseline plasma HIV RNA level Incidence of lipodystrophy and other metabolic complications in three ...

Phase N/A

Oral Human Papillomavirus Infection in HIV-infected Men

Human papillomavirus (HPV)-infection belong to the most common sexually transmitted diseases worldwide. Estimated prevalences of subclinical genital HPV-infection in the immunocompetent sexually active population range from 10 to above 50%. Genetic or iatrogenic immunosuppression is known to play a decisive role in the initiation of a variety of cutaneous neoplasias ...

Phase N/A

A Prospective Cohort of Children With HIV Infection

This is a long term cohort study that was started in 2002. Currently, there are 120 children enrolled in the study and are receiving HIV care according to standard practice set by the Thai Ministry of Public Health. HIV-infected parents also receive care at the same clinic.

Phase N/A

Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies

In order to carry out research procedures on the plasma or mononuclear components of blood, it is often necessary to obtain larger quantities of plasma or mononuclear cells than can be safely obtained by simple phlebotomy. These components can be easily and safely obtained using apheresis procedures in the Clinical ...

Phase N/A

The Quality of Life of Patients With Severe Illnesses

Lately researchers and clinicians have emphasized the health related quality of life. Several reasons account for this trend. First of all, the advanced medical practices have contributed to the increased life expectancy. Secondly, the pattern of diseases has shifted from high acuity to chronicity. Therefore, the effectiveness of health care ...

Phase

SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era

SCOPE is an observational, prospective study of HIV-1 infected volunteers designed to provide a specimen bank of samples with carefully characterized clinical data. Samples from SCOPE will be used to examine: Virologic, immunologic, and host factors involved in the natural control of HIV-1 infection (long term non-progression and/or virologic control ...

Phase N/A

Development of Resistance Mutations in Pregnant HIV-Positive (+) Women Following Perinatal Antiretroviral Therapy in Israel

The project will be performed in collaboration with the Israeli National HIV Reference Center Laboratory, which maintains a national bank of HIV-positive blood samples, and with HIV/AIDS treatment centers located throughout Israel. An initial survey will identify retrospectively those HIV+ women who were given antiretroviral therapy while pregnant and stopped ...

Phase N/A