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Acute Respiratory Distress Syndrome (ARDS) Clinical Trials

A listing of Acute Respiratory Distress Syndrome (ARDS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (74) clinical trials

Bioequivalence Study of Generic Fluticasone Propionate 100 µg and Salmeterol Xinafoate 50 µg Inhalation Powder Compared with Advair Diskus® 100/50 in Subjects with Asthma

Phase N/A

Inflammation and Distribution of Pulmonary Ventilation Before and After Tracheal Intubation in ARDS Patients

We will conduct a prospective clinical protocol in patients admitted to the ICU of the Hospital Clnico UC-Christus, Santiago de Chile, with diagnosis of acute hypoxemic respiratory failure, but who are still ventilating spontaneously. Clinical data: After hospital admission, patients who meet inclusion/exclusion criteria will be asked to consent to ...

Phase N/A

A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients

Acute respiratory distress syndrome (ARDS)over the years in the treatment policy has been confirmed that: with low tidal volume to achieve lung protection strategy and high positive end-expiratory pressure (PEEP), both can effectively reduce the mortality rate. And increase PEEPthe alveolar pressure is greater than the atmospheric pressure when exhaledSo ...

Phase N/A

Pediatric Acute Respiratory Distress Syndrome Ventilation Bundle

We implement a PARDS ventilation bundle compliant with PALICC recommendations. The bundle contains a daily checklist for ventilation targets and reference tables listing targeted tidal volumes and end expiratory pressure-fraction of inspired oxygen titration. We will recruit mechanically ventilated patients who meet PARDS criteria. After a one-month implementation period, we ...

Phase N/A

N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome

Objectives / Research Aims The overall objectives of this study are to demonstrate whether a protocol for the early use of inhaled N-acetylcysteine improves mortality, ventilator days, ICU days, hospital stay, as well as the need for other "rescue" modalities, such as use of advanced ventilator modalities (such as airway ...

Phase N/A

Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates

Acute respiratory distress syndrome (ARDS) is one of the serious complications in critically ill neonates. It can result in severe hypoxemia refractory to mechanical ventilation. There are few options for mechanical ventilation for such situations such as high frequency oscillation ventilation and extracorporeal membrane oxygenation. The aim of the present ...

Phase N/A

Molecular Epidemiology of ARDS

BACKGROUND The acute respiratory distress syndrome (ARDS) remains a major cause of morbidity and mortality around the world. In the United States alone there are 150,000 cases per year. Although there have been significant scientific advances in understanding the clinical and pathophysical aspects of the syndrome, there is as yet ...

Phase N/A

Expiratory Flow Limitation Assessment

This study intended to assess the expiratory flow limitation (EFL) during tidal breath in patients intubated in intensive care unit (ICU) for moderate or severe acute respiratory distress syndrome (ARDS). EFL is defined as the lack of increase in expiratory flow in response to an increase in alveolar-to-atmospheric pressure gradient. ...

Phase N/A

WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE

The purpose of this study is to describe, in a large population of ICU patients the burden of, management and spectrum of approaches to weaning from ventilation, in patients that require invasive mechanical ventilation for any reason, for a time period of at least 24 hours. It will answer the ...

Phase N/A

Incidence of Dyssynchronies in Early ARDS

Measurements Physiological measurements Airway pressure, esophageal pressure, electrical activity of the diaphragm and flow Flow and airway pressure signal will be recorded from the ventilators by connecting the ventilator to a laptop computer if possible. Recording these data simultaneously with esophageal pressure or electrical activity of the diaphragm (see later ...

Phase N/A