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Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (70) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT00626990?term=RTOG-0834&rank=1

Phase

Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology

Gliomas are the most common primary brain tumors in adults; most are high-grade and have a high level of mortality. The standard treatment is to kill or remove the cancer cells. Of course, this can only work if the surgeon or radiologist can find these cells. Unfortunately, there are inevitably ...

Phase N/A

Correlation Between SV2A Expression in Tumour Tissue and Efficacy of Levetiracetam in Glioma Patients With Epilepsy

Levetiracetam is a relatively novel anti-epileptic drug (AED), which has proven to be effective and well tolerated in many glioma patients with otherwise pharmacoresistant epilepsy. Moreover, levetiracetam has neither enzyme-inducing nor enzyme-inhibiting properties, which makes the drug particularly attractive for brain tumour patients, as they frequently receive chemotherapy and/or corticosteroids. ...

Phase

Radiation Therapy Temozolomide Tamoxifen and Carboplatin in Treating Patients With Malignant Gliomas

OBJECTIVES: - Determine the progression-free and overall survival of patients with supratentorial malignant gliomas (WHO grade III or IV) receiving radiotherapy with concurrent and adjuvant temozolomide, tamoxifen citrate, and carboplatin. - Determine the acute and delayed treatment-related toxicities in these patients. - Determine tumor response in patients with postoperative measurable ...

Phase

Establishment of a Brain and Spinal Tumor Tissue Bank

Glioblastoma multiforme (GBM) is the most common and lethal primary Brain and Spinal Tumor in adults. It is nearly uniformly fatal, with a median survival of approximately one year, despite modern treatment modalities. Efforts to understand why some patients live longer or shorter than the average may provide insights into ...

Phase N/A

A Phase I Dose Escalation Study for Patients With Recurrent Malignant Gliomas

Recurrent malignant gliomas are uniformly fatal, and there has been no standard treatment in this setting. Radiation therapy remains the main treatment. Although the efficacy of systemic chemotherapy has not been well defined, studies have shown that some new agents such as gefitinib and vandetanib have promising effects either as ...

Phase

Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components

Existing methods of contouring tumours for radiation therapy involve manual interpretations of qualitative diagnostic images. These methods, being qualitative, do not offer a consistent and reproducible platform for contouring, making it difficult to evaluate the effects of contouring choices on treatment outcome. T2 component analysis in MRI has the potential ...

Phase N/A