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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (231) clinical trials

Efficacy and Safety of Tx360 Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

This is a phase III, multi-center, randomized, double-blind, placebo-controlled, prospective, clinical trial examining the outcomes of subjects with chronic migraine headache who are treated with 0.3cc of 0.5% bupivacaine bilaterally vs 0.3cc of sterile water bilaterally, each delivered to the mucosal surface of the SPG through each nare with the ...


Strength and Awareness in Action: an Intervention for Post-Acute TBI Headaches (SAA-TBI)

A signature injury being sustained by Veterans from recent conflicts is mild traumatic brain injury (mTBI). For some, this condition is associated with multiple disabling post-concussive symptoms, including post-concussive headaches (PCH). PCHs are notoriously resistant to medication alone, and are associated with increased muscle tension, avoidance of physical activities, and ...

Phase N/A

Integrative Migraine Pain Alleviation Through Chiropractic Therapy

Chiropractic care is a commonly used therapeutic intervention for the treatment of pain disorders, and some smaller studies have shown that it might be helpful for migraines. This pilot study will use a comprehensive model of chiropractic treatment which can include soft tissue mobilization, spinal manipulation, and postural and spinal ...

Phase N/A

Headache Inducing Effect of Cromakalim in Migraine Patients

To investigate the role of KATP channels on the cerebral hemodynamic in migraine patients.

Phase N/A

Magnesium Partenium Andrographis Co-enzyme Q10 and Riboflavin (PACR) in Migraine Prophylaxis

Migraine is a highly disabling disorder that affects hundreds of millions of people around the world. Yet, a little number of prophylactic treatments are available still now. The limited number of available drugs leads to a wide use of nutraceutical compounds in migraine therapy. To improve the efficacy, some of ...

Phase N/A

Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics

During labor and delivery, pregnant women may choose to receive pain relief called epidural analgesia, which is the delivery of a numbing agent through the back and into a body space around the spinal column. This numbs the area of the stomach and the pelvis. Typically the numbing agent is ...


Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years With OLE

To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment). Screening will be performed based on the inclusion exclusion criteria specified in the study protocol. ...


RELAXaHEAD for Headache Patients

The goal of this research is to assess the utility of smartphone-based progressive muscle relaxation (PMR) for the treatment of headaches. While there are many commercially available electronic diary and mind-body intervention apps for headache, there is little data showing their efficacy. RELAXaHEAD app incorporates the electronic PMR that was ...

Phase N/A

Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines

The purpose of this study is to determine if there are genetic variations that can explain a genetic basis for cyclic vomiting syndrome (CVS), various phenotypes of CVS (e.g. menstrual, Sato, calendar-tied) and migraine headaches (e.g. with aura, without aura, hemiplegic migraine). This information will allow physicians to improve care ...

Phase N/A

Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine

The purpose of this study is to determine if there are significant differences in the side effects related to memory, repetition and recall among these three drugs when used in a pediatric population.

Phase N/A