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Lupus Clinical Trials

A listing of Lupus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (145) clinical trials

Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)

Discoid Lupus Erythematosus (DLE ) and systemic lupus erythematosus (SLE) can be devastating diseases with a significant impact on quality of life. DLE is currently treated with potent topical steroids, antimalarials, and immunosuppressants. Recent research has determined that DLE is a Th1 mediated disease. There is increasing evidence that JAK ...

Phase N/A

Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study

Participants will be randomly divided into two groups. One group will receive a nicotine patch to use for approximately 7 months; the other group will receive placebo for nicotine patches to use for the same time period. Both groups will be contacted weekly by phone for the first 3 weeks ...

Phase

Use of Immunosuppressive Therapy for Sarcoidosis

Patients receiving one or more cytotoxic or other immunosuppressive drug will be observed

Phase N/A

Retrospective Analysis of Renal Prognosis in Patients With Chronic Kidney Disease

During 1993 and 2006, a total of 987 patients older than 20 years underwent native kidney biopsy at the Renal Division of this hospital. 404 patients with membranoproliferative glomerulonephritis and mesangioproliferative glomerulonephritis, and patients with secondary glomerulonephritis or other renal pathologies, such as diabetic nephropathy, lupus nephritis, rapid progress glomerulonephritis, ...

Phase N/A

The Iguratimod Effect on Lupus Nephritis (IGeLU)

This study is a 52-week, randomized, open, active-controlled trial of patients with active diffused lupus nephritis, to assess the efficacy and safety of a novel chemical synthetic agent iguratimod. The subjects will randomly receive iguratimod or cyclophosphamide followed with azathioprine, both combined with steroids.

Phase

Long Non Coding RNA in Complications of Systemic Lupus

the precise role of RNA in setting of this complication in systemic lupus erythematosus (SLE) is largely unknown

Phase N/A

Photoprovocation Testing in Subjects With Cutaneous Lupus

Photosensitivity is well documented among lupus patients and is one of the diagnostic criteria for systemic lupus erythematosus (SLE). Photosensitivity is highly prevalent in lupus and has a wide range of clinical presentations. However, photosensitivity is a poorly defined in lupus and its pathogenesis is not well understood. The purpose ...

Phase N/A

Accuracy Feasibility and Acceptance of CGM Lupus

This is a prospective monocenter, non-randomised, open-lable single-group intervention diagnostic trial on the accuracy, reliability and feasibility of the continuous glucose monitoring system in critically systemic lupus erythematosus (SLE). Newly developed technologies for continuous glucose monitoring in critically SLE patients may improve glycemic control and reduce glucose variability. Critically SLE ...

Phase N/A

Study During Pregnancy of Expression of miRNAs in RA or SLE

Rheumatoid arthritis (RA) is a systemic disease, which mainly targets joints and results in osteoarticular destruction and serious disability. When clinical symptoms (painful and swollen joints) occur, the innate and adaptive immune responses against self antigens have already been largely amplified. This might explain that even when RA patients are ...

Phase N/A

Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases

Timeframe Collection of DNA for discovery cohort until 05/2016 Data analysis until 12/2014 for pyoderma gangrenosum, until 12/2016 for other NMID Report and data presentation early 2015 for PG, 2017 for other NMID

Phase N/A