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Anemia Clinical Trials

A listing of Anemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (468) clinical trials

Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth

Data for the needs assessment and pilot trial will be collected from the patients via validated surveys, qualitative methods (e.g., interviews and focus groups), and medical record abstraction. The study will utilize a Hybrid Effectiveness-Implementation design that will blend both a new intervention to impact the effectiveness of hydroxyurea, text ...

Phase N/A

A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects

The purpose of this study is to evaluate the efficacy and safety of molidustat in non-dialysis subjects with renal anemia who are not treated with Erythropoiesis-Stimulating Agents (ESAs).


Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

PRIMARY OBJECTIVES: I. To assess the safety, tolerability and feasibility of administering metformin hydrochloride (metformin)/ritonavir combination therapy in patients with relapsed/refractory multiple myeloma or relapsed/refractory chronic lymphocytic leukemia. SECONDARY OBJECTIVES: I. To characterize the clinical activity of this two-drug combination by assessing disease response, response duration, and (in relapsed/refractory multiple ...


Liver Fibrosis in Sickle Cell Disease

Liver biopsy is the gold standard to examine the liver for iron deposits and histology. However, liver biopsy is invasive and involves a risk of bleeding and pain. Biopsy may also miss significant pathology if the small biopsy specimen is taken from an uninvolved part of the liver. Non-invasive techniques ...

Phase N/A

Gene Therapy for Fanconi Anemia

PRIMARY OBJECTIVES: I. To determine the safety of lentiviral gene transfer for patients with Fanconi anemia complementation group A. SECONDARY OBJECTIVES: I. To determine the feasibility and efficacy of filgrastim (G-CSF) and plerixafor mobilization in FA patients. II. To determine the feasibility and efficacy of lineage depletion of bone marrow ...


A clinical trial to evaluate treatments for patients with Aplastic Anemia, MYELODYSPLASTIC SYNDROME, Lymphoma, Preleukemia, leukemia

Background The requirement for licensure of human cell and blood products became part of the FDA final rules for Human Cells, Tissues, and Tissue-Based Products (HCT/Ps) (March 29, 2004 and May 25, 2005) in an effort to prevent transmission of communicable disease, minimize contamination and preserved integrity and function during ...


Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

Allogeneic hematopoietic stem cell transplantation (aHSCT) can cure patients with a variety of bone marrow failure syndromes (BMFS) including severe aplastic anemia (SAA), paroxysmal nocturnal hemoglobinuria (PNH) or myelodysplastic syndrome (MDS) associated with cytopenias. Patients with BMFS have traditionally been transplanted with bone marrow (BM) as a stem cell source. ...


Paroxysmal Nocturnal Hemoglobinuria (PNH) Registry

Collection of data to evaluate safety and characterize progression of Paroxysmal Nocturnal Hemoglobinuria (PNH).

Phase N/A

Validating Pain Scales in Children and Young Adults

BACKGROUND Pain is a common symptom among children with a variety of medical illnesses. Currently, a number of rating scales are used to assess pain interference and pain severity in adults. However, relatively few measures assessing these variables have been validated for use with children and adolescents, and existing tools ...

Phase N/A

Heart Arteries and Sickle Cell Disease / Coeur Art res DREpanocytose

Sickle cell disease (SCD), one of the lost common genetic diseases worldwide, is caused by a mutation in the globin gene. Most patients with this disease are homozygous for the S allele (SS), whereas others have inherited a S allele with another mutation in the globin gene. In addition to ...

Phase N/A