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Post-Partum Depression Clinical Trials

A listing of Post-Partum Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (11) clinical trials

The purpose of the study is to examine how mother's mental health experiences might influence brain function in response to her infant and how this might be related to the parent-infant relationship. There will be 2 study visits over 7 to 10 days. The first visit is 3 to 4 ...

Phase N/A

To determine if SAGE-547 Injection infused intravenously for 60 hours reduces depressive symptoms in subjects with postpartum depression (PPD) compared to placebo injection

Phase N/A

The PPD-202 Trial is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study evaluating the efficacy, safety and pharmacokinetics of SAGE-547 Injection in the treatment of adult female subjects with severe postpartum depression.


The purpose of this study is to test an investigational drug called SAGE-547 (Allopregnolone) to determine if it is safe and has any effect on moderate and/or severe postpartum depression. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA).

Phase N/A

The Role of Hormones in Postpartum Mood Disorders

The appearance of mood and behavioral symptoms during pregnancy and the postpartum period has been extensively reported. While there has been much speculation about possible biologically based etiologies for postpartum disorders (PPD), none has ever been confirmed. Preliminary results from two related studies (protocols 90-M-0088, 92-M-0174) provide evidence that women ...

Phase N/A

Screening Evaluation for Women With Postpartum Depression

Controversy exists regarding the relevance of changes in gonadal steroids for postpartum-onset depressions. The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols that examine the role of gonadal steroids in postpartum-onset depressions (PPD) and for the collection ...

Phase N/A

Trial to Evaluate the Effect of Home-Based Peer Support on Maternal-Infant Interaction Infant Health Outcomes and Postpartum Depression (PPD)

This controlled study will help establish the link between support for maternal caregiving, maternal-infant interaction, infant neuroendocrinology and infant cognitive and social development. The primary hypothesis predicts that home-based peer support will improve maternal-infant interactions. Secondary hypotheses predict that home-based peer support will: improve infants' cognitive development; improve infants' social ...

Phase N/A