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Autonomic Nervous System Clinical Trials

A listing of Autonomic Nervous System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (25) clinical trials

Autonomic Nervous System Activity and Oculocardiac Reflex.

Pulling the eyeball during ophthalmic surgery provokes decrease in heart rate. This phenomenon is called oculocardiac reflex. In some patients asystole may occur. Other cardiac features of this reflex include hypotension, dysrhythmias, atrioventricular block. These cardiovascular disturbances may lead to decreased perfusion and ischemia of vital organs. Patients with existing ...

Phase N/A

Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy

Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety of symptoms including sensation impairments and weakness. The impairments are usually most evident in the feet and ...

Phase N/A

Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension

Neurogenic orthostatic hypotension (NOH) is a debilitating condition associated with reduced quality of life, impaired function and is also an independent predictor of mortality(Bendini et al., 2007; Cordeiro et al., 2009; Rose et al., 2006). NOH is clinically defined as a sustained reduction in systolic blood pressure (SBP) 30mmHg within ...

Phase N/A

Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction

Sudden cardiac death (SCD) is the most common single cause of death in the industrialized world. Patients after myocardial infarction (MI) are at increased risk of SCD. Current guidelines recommend prophylactic ICD-implantation in post-MI patients with reduced left ventricular ejection fraction (LVEF 35%). However, the majority of arrhythmic deaths after ...

Phase N/A

The Effect of Thoracic Spinal Manipulation on Autonomic Nervous System

Several studies have shown that spinal manipulative therapies had an immediate effect on autonomic nervous system activity (sympathoexcitatory effect) and on pressure pain sensitivity (hypoalgesic effect). Only one study assessed and found a correlation between these effects. Despite this interest, no one has assessed i) if these effects last over ...

Phase N/A

Hypoglycemia and Autonomic Nervous System Function- B2

Participants are admitted for two days and two nights to an inpatient clinical research center for performance of study procedures. On Day 1, two hyperinsulinemic hypoglycemic (50 mg/dl) clamps are performed - an AM clamp from about 9 to 11 am and a PM clamp from about 1 to 3 ...

Phase N/A

Autoimmune Basis for Postural Tachycardia Syndrome

Postural tachycardia syndrome (POTS) is a debilitating disorder resulting from cardiovascular autonomic dysfunction, has many causes and is very difficult to treat effectively. The investigators have identified the presence of autoantibodies (immune proteins) directed against some receptors of the autonomic nervous system that can cause patient's symptoms on standing. The ...

Phase N/A

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

This is an inpatient study that requires at least four days of admission to the Vanderbilt Clinical Research Center. Autonomic failure patients will be placed on a fixed diet during the admission and will have routine tests performed for screening and clinical characterization. Patients will then receive intravenous angiotensin-(1-7) or ...

Phase N/A

Pain In Neuropathy Study

Very little is currently known about why some patients with peripheral neuropathy develop neuropathic pain, whilst others do not. It is anticipated that this study will begin to identify features of the peripheral neuropathy, which are and are not, associated with the development and intensity of neuropathic pain and therefore ...

Phase N/A

Investigation of the Rewarming og the Fingers After Cooling and the Autonomic Nervous System in Raynaud's Phenomenon

Raynaud's phenomenon: Raynaud's phenomenon is defined by vasospasms occurring in the fingers, toes, nose, ears or tongue lasting for minutes to hours. The attacks of vasospasms are provoked by cold exposure or stressful emotions and present themselves as well demarcated pallor of the skin and may include desensitization of the ...

Phase N/A