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Cardiac Surgery Clinical Trials

A listing of Cardiac Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (308) clinical trials

Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery

Hypothermia increases sympathetic activation, promotes tachycardia, and causes hypertension all of which may increase the risk of myocardial injury. Moderate perioperative hypothermia is now uncommon, but mild hyperthermia (35.5C) remains common. Whether aggressive warming to a truly normothermic level (37C) improves outcomes remains unknown.

Phase N/A

Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex)

The drug Dexmedetomidine will be investigated in 72 patients (men and women) undergoing elective cardiac or abdominal surgery. The study medication will be administered perioperatively by intravenous infusion continuously (at the longest 48 h) to prevent/reduce the rate of Delirium and the incidence of postoperative cognitive deficit (POCD). A non-surgical ...


The Pilot Project Development Of MEdical Rehabilitation System in Russian Federation

The program is performed in the in-patient and out-patient rehabilitation departments in 13 regions of the Russian Federation (total 244 departments). The basic goals of the Programme are: To develop the system of organizations for medical rehabilitation providing succession of rehabilitation care in Russia with covering all needs. To improve ...

Phase N/A

The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery

Prospective, consecutive study of patients undergoing cardiac surgery in Heart and Vascular Center, Semmelweis University, Budapest. Registered data: Anamnestic and demographic data Liver dysfunction prior surgery, etiology of liver dysfunction Perioperative clinical data: laboratory tests, imaging, haemodynamic measures risk prediction score of the American Society of Anesthesiologists(ASA), EUROpean System for ...

Phase N/A

Prevalence of Hypovolemia and Heart Failure in Non-cardiac Surgery

Preoperative transthoracic echocardiography (TTE) is conducted in 100 individuals. Biventricular function (i.e. systolic and diastolic properties), left ventricular filling pressures and level of venous return are assessed by TTE. Moreover Troponine T and Nt-proBNP, ECG are collected.

Phase N/A

Dynamic SAX vs Conventional LAX in Radial Artery Cannulation.

When performing vascular cannulation such as radial artery cannulation, ultrasonography (US) helps proper positioning of the tip of needle in the vascular lumen, which facilitating cannulation of the catheter and successful pressure monitoring. Conventionally, short-axis out-of-plane (SAX) and long-axis in-plane (LAX) views are commonly used method to image the target ...

Phase N/A

Use of a Support Bra to Reduce Pain and Improve Surgical Healing in Women Undergoing Sternotomy for Cardiac Surgery

Participants will be randomized to one arm of the study. One group will be fitted for a support bra and will be asked to wear this bra 24 hours a day for their 6 week post-course. They will submit to 3 questionnaires (at hospital discharge, at 3 weeks post-op and ...

Phase N/A

Albumin in Cardiac Surgery

The use of cardiopulmonary bypass (CPB) between two study solutions: albumin solution with the final concentration of 4% and Ringer's acetate solution. The trial consists of two phases as follows. For each patient, one and the same study solution will used in both phases of the trial according to randomization. ...


Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool

Elderly patients undergoing surgery are more vulnerable to adverse postoperative outcomes due to advanced age, frailty, and concomitant medical conditions. Adverse cognitive outcomes such as postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are frequently encountered in older surgical patients, and are associated with increased morbidity and mortality. Since there ...

Phase N/A

Effects of Extra Corporeal Circuit Prime on Electrolytes Balance and Clinical Outcome Following Cardiac Surgery

About 6000 heart operations are performed in Sweden every year. A heart-lung machine is used almost exclusively in all heart operations. This machine fills the role of heart and lungs during surgery while the heart is stopped. The extra corporeal circuit (ECC) prime results in hemodilution, as assessed from the ...

Phase N/A