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Cardiac Surgery Clinical Trials

A listing of Cardiac Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (301) clinical trials

The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). There are no new or "experimental" procedures being tested ...

Phase

A clinical study of the TAXUS® Liberté® Paclitaxel-Eluting Coronary Stent System which was previously approved by the FDA. Patient Inclusion Criteria: >years of age Patients that need a stent in the coronary arteries Patient Exclusion Criteria: Cannot receive the protocol required dual antiplatelet therapy Currently taking warfarin or similar anticoagulant ...

Phase

Optilene Suture for Coronary Artery Bypass Graft Surgery

Coronary artery bypass graft (CABG) surgery is one of the most common elective surgical procedure. In total 40.000 CABGs have been performed yearly in Germany in 2012 and 2013 which presents 60% of all cardiac surgical interventions. Coronary artery bypass grafting is performed for patients with coronary artery disease (CAD) ...

Phase N/A

The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery

Rationale: Acetylsalicylic acid (ASA) is used to prevent the occlusion of grafts placed during coronary artery bypass grafting surgery (CABG) and to reduce the incidence of atherothrombotic events during follow-up. Graft occlusion occurs predominantly in saphenous vein grafts (SVGs) and can result in symptoms of chest pain, myocardial infarction (MI) ...

Phase

FORE-SIGHT Tissue Oximeter During Cardiac Surgery

The purpose of this research study is to collect data from a tissue oximeter device that measures brain oxygen saturation simultaneous with data from the same device that monitors skeletal muscle during cardiac surgery. This monitoring will allow for continuous, non-invasive, and earlier assessment of perfusion abnormalities/hypoperfusion. Two sensors from ...

Phase N/A

Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients

The ExeQOL study is an ancillary study of the ExSTRESS trial (www.clinicaltrials.gov identifier: NCT01969149). The ExSTRESS trial is a phase II/III randomized-controlled trial that aim at assessing intravenous exenatide versus insulin for perioperative glycemic control in CABG surgery. The phase II of the ExStress trial will assess the safety and ...

Phase

Active Clearance Technology (ACT) II German Multicenter Trial

Complications from RBS are defined as those requiring re-operation or surgical interventions to evacuate blood, blood clot, bloody fluid, and air accumulation within the operative site after closure of the surgical wound. This is a prospective multicenter observational post-market study with a retrospective component. The study is open to up ...

Phase N/A

Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass

Angion Biomedica Corp. has developed a small molecule hepatocyte growth factor/scatter factor (HGF/SF) mimetic, termed BB3, which exerts significant nephroprotective effects in several preclinical renal injury models. Angion intends to develop BB3 as a therapy to prevent and/or treat acute kidney injury. BB3 is a new molecular entity and the ...

Phase

Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation

In this open-label, prospective, randomized pilot study, patients who develop atrial fibrillation after isolated coronary artery bypass grafting surgery will be identified. Patients with persistent atrial fibrillation (>12 hours) or recurrent sustained atrial fibrillation (>2 episodes of atrial fibrillation lasting longer than 30 minutes) will be candidates for inclusion. Upon ...

Phase

Investigation of Fluid- and Electrolyte Balance in Post Cardiac-surgery Patients

Critically ill patients need intravenous fluid therapy in order to correct or prevent problems with their fluid and/or electrolyte status and for renal protection. The decision for the optimal composition and amount of IV-fluids can be difficult and complex. It is well known that errors in fluid- and electrolyte management ...

Phase N/A