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Cardiac Surgery Clinical Trials

A listing of Cardiac Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (238) clinical trials

Noninvasive Measurements of Renal Perfusion During Cardiac Surgery

Acute kidney injury (AKI) is an unfortunately common complication of cardiac surgery that occurs in up to 40% of patients and results in increased mortality, prolonged ICU and hospital length of stay. AKI after cardiac surgery is not a benign complication, increasing mortality from 1% to 19% in those with ...

Phase N/A

Vasoplegic Syndrome in Cardiac Surgery

Vasoplasmic syndrome in cardiac surgery is one of the major postoperative complications.This syndrome is characterized by persistent low blood pressure despite an optimization of preload and inotropism.

Phase N/A

Evaluation of the Association Between Pre-existing Endothelial Dysfunction and the Onset of Vasoplegia During Cardiac Surgery With Cardiopulmonary Bypass

Cardiac surgery patients have many risk factors for endothelial dysfunction (hypertension, atherosclerosis, dyslipidemia, chronic renal failure ...). It is likely that a significant number of patients suffering from a preexisting endothelial dysfunction. This endothelial dysfunction can be assessed by a molecular approach (determination of NO, ICAM1, VCAM1, IL8, endothelial microparticles ...

Phase N/A

A Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery

This is a prospective, single-center case control comparison of expression of target genes responsible for energy utilization, mitochondrial function and oxidative stress and levels of histone acetylation/ DNA methylation in obese and non-obese adult cardiac surgery patients.

Phase N/A

Erythrocyte Transfusion Based on the Measurement of Central Venous Oxygen Saturation in Postoperative Cardiac Surgery

Postoperative erythrocytes transfusion is associated with morbidity and excess mortality, which should lead to ask the indication for RBC transfusions only on metabolic needs. Currently, the majority of studies used to put hemoglobin values indicating red cell transfusions. Two observational studies have confirmed that a transfusion strategy based on a ...

Phase N/A

Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery

Hypothermia increases sympathetic activation, promotes tachycardia, and causes hypertension all of which may increase the risk of myocardial injury. Moderate perioperative hypothermia is now uncommon, but mild hyperthermia (35.5C) remains common. Whether aggressive warming to a truly normothermic level (37C) improves outcomes remains unknown.

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The Pilot Project Development Of MEdical Rehabilitation System in Russian Federation

The program is performed in the in-patient and out-patient rehabilitation departments in 13 regions of the Russian Federation (total 244 departments). The basic goals of the Programme are: To develop the system of organizations for medical rehabilitation providing succession of rehabilitation care in Russia with covering all needs. To improve ...

Phase N/A

The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery

Prospective, consecutive study of patients undergoing cardiac surgery in Heart and Vascular Center, Semmelweis University, Budapest. Registered data: Anamnestic and demographic data Liver dysfunction prior surgery, etiology of liver dysfunction Perioperative clinical data: laboratory tests, imaging, haemodynamic measures risk prediction score of the American Society of Anesthesiologists(ASA), EUROpean System for ...

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Dynamic SAX vs Conventional LAX in Radial Artery Cannulation.

When performing vascular cannulation such as radial artery cannulation, ultrasonography (US) helps proper positioning of the tip of needle in the vascular lumen, which facilitating cannulation of the catheter and successful pressure monitoring. Conventionally, short-axis out-of-plane (SAX) and long-axis in-plane (LAX) views are commonly used method to image the target ...

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Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool

Elderly patients undergoing surgery are more vulnerable to adverse postoperative outcomes due to advanced age, frailty, and concomitant medical conditions. Adverse cognitive outcomes such as postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are frequently encountered in older surgical patients, and are associated with increased morbidity and mortality. Since there ...

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