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Cardiac Surgery Clinical Trials

A listing of Cardiac Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (298) clinical trials

The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). There are no new or "experimental" procedures being tested ...

Phase

A clinical study of the TAXUS® Liberté® Paclitaxel-Eluting Coronary Stent System which was previously approved by the FDA. Patient Inclusion Criteria: >years of age Patients that need a stent in the coronary arteries Patient Exclusion Criteria: Cannot receive the protocol required dual antiplatelet therapy Currently taking warfarin or similar anticoagulant ...

Phase

Active Clearance Technology (ACT) II German Multicenter Trial

Complications from RBS are defined as those requiring re-operation or surgical interventions to evacuate blood, blood clot, bloody fluid, and air accumulation within the operative site after closure of the surgical wound. This is a prospective multicenter observational post-market study with a retrospective component. The study is open to up ...

Phase N/A

Optilene Suture for Coronary Artery Bypass Graft Surgery

Coronary artery bypass graft (CABG) surgery is one of the most common elective surgical procedure. In total 40.000 CABGs have been performed yearly in Germany in 2012 and 2013 which presents 60% of all cardiac surgical interventions. Coronary artery bypass grafting is performed for patients with coronary artery disease (CAD) ...

Phase N/A

SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX -Trial).

Over a million patients undergo open heart surgery annually and this number is likely to accelerate as the population ages and the prevalence of diabetes and cardiovascular disease continue to increase. Unfortunately, death, organ failure, and other serious complications are all too frequent following open heart surgery, especially in some ...

Phase

Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery

The investigator goal is to evaluate the effects of intraoperative and postoperative dexmedetomidine sedation (versus placebo after cardiac surgery.

Phase

Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass

This is a prospective, multicenter, randomized, double-blind, placebo-controlled study. The purpose of this study is to determine the safety and effectiveness of human-derived antithrombin III (AT-III [Human]) supplementation prior to high-risk, non-emergency, cardiac surgery with cardiopulmonary bypass (CPB). A total of 404 adult subjects undergoing CPB who meet the study ...

Phase

Octaplas Pediatric Plasma Replacement Trial

The purpose of this study is to investigate the safety, tolerability and efficacy of octaplas in pediatric patients who require replacement of multiple coagulation factors. Replacement of multiple coagulation factors in pediatric patients with acquired deficiencies due to liver disease and in pediatric patients requiring cardiac surgery or liver surgery.

Phase

Measurement of Pulmonary Transit Time by Echocardiography: Comparison With Cardiac MRI

Study Procedures The measurement of PTT and PBV has been described in detail in our prior protocol. These calculations and techniques are identical for the current study. In addition, we may place additional regions of interest (ROIs) during the off-line analysis, but this step would not influence the data acquisition ...

Phase N/A

Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol

The objective of this investigation is to compare the cardioprotective effects and safety of two cardioplegic solutions, HTK Cardioplegic Solution (Custodiol) and Custodiol-N in patients undergoing aortic valve surgery. The study design is a prospective, double blind, multicenter, randomized, Phase III comparison study intended to demonstrate superiority in surgical outcome ...

Phase