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Hepatoblastoma Clinical Trials

A listing of Hepatoblastoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (14) clinical trials

Collection of Blood From Patients With Cancer

Background: - Correlative studies performed on biospecimens of human subjects can be used to investigate the biology of solid tumors, inform the development of new strategies for treating those cancers, and evaluate these new therapeutic approaches. Specific areas of interest include, but are not limited to: - the underlying mechanisms ...

Phase N/A

Mobilization of Mesenchymal Stem Cells During Liver Transplantation

Mesenchymal stem cells (MSCs) are a known immune modulator with significant immunosuppressive effects. MSCs have emerged as a promising frontier in human clinical trials. MSCs have been shown to be non-immunogenic making them capable of transplantation across allogeneic barrier. These qualities make MSCs an ideal candidate to study if they ...

Phase N/A

Combined Modality Therapy in Hepatoblastoma: South Egypt Cancer Institute Experience

Background: Hepatoblastoma (HB) is the most common malignant liver tumor in children, with an incidence of 0.7 to 1 per million children <15 years of age. Till 1970s, surgery was the primary modality of treatment of HB. Unfortunately, up to 60% of the patients present in an unresectable stage. Later, ...

Phase N/A

Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC)

In the currently ongoing retrospective aspect of the study, we will obtain pathologic tumor explant specimens from the tumor explant population from 8/1/1994 to 12/31/2005. We will prepare 5-10 slides from each tumor explant block and measure HIF-1α using immunohistochemical staining. We will also be performing a retrospective chart review ...

Phase N/A

A Treatment of Unresectable Hepatocellular Carcinoma With TheraSphere

The purpose of this protocol is to provide supervised access at this institution to TheraSphere® treatment for a heterogeneous population of patients with unresectable primary liver tumors, with the liver being the only dominant site of disease. Based on experience gained in previous studies and well-established interventional radiology techniques, this ...

Phase N/A

Microwave Ablation of Resectable Liver Tumors

Minimally invasive surgical alternatives are becoming more attractive for the treatment of malignancy.The goal is to reduce morbidity and mortality and increase the ability to treat patients in the outpatient setting. Image-guided ablation is becoming an attractive alternative because of its relative low cost, its ability to provide large regions ...

Phase N/A

Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma

Liver cancer is a deadly cancer that is typically hard to diagnose and treat. The currently used blood marker for the clinical diagnosis of liver cancer is alpha-feto protein (AFP), which misses 40-60% of patients with liver cancer because it lacks sufficient specificity and sensitivity. The purpose of this study ...

Phase N/A

Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

OBJECTIVES: - Provide supervised access to treatment with yttrium Y 90 glass microspheres (TheraSphere®) to eligible patients with cancer of the liver who are not candidates for surgical resection. - Evaluate patient experience and toxicities associated with yttrium Y 90 glass microspheres (TheraSphere®) treatment. OUTLINE: This is a humanitarian device ...

Phase N/A

Radiolabeled Glass Beads in Treating Patients With Metastatic Liver Cancer That Cannot Be Removed by Surgery

OBJECTIVES: - Provide supervised access to treatment with yttrium Y 90 glass microspheres (TheraSphere®) to eligible patients who are not candidates for surgical resection of metastatic intrahepatic carcinoma. - Evaluate patient experience and toxicities associated with yttrium Y 90 glass microspheres treatment. OUTLINE: This is a humanitarian device exemption use ...

Phase

Genetic Susceptibility or Resistance to Hepatitis B Virus in the Chinese Population

OBJECTIVES: - Study how different outcomes of hepatitis B exposure and infection are affected by host genetic factors in the Chinese population. OUTLINE: This is multicenter study. Participants complete health questionnaires about personal and family health history and eating, drinking, and smoking habits. Blood samples from participants are collected and ...

Phase N/A