Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Hepatoblastoma Clinical Trials

A listing of Hepatoblastoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (139) clinical trials

Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer

Each cycle will last for 4 weeks. Sorafenib and trametinib will be administered orally on continuous basis. During the first cycle sorafenib will be started on day 1 and trametinib on day 8 to improve tolerance. Participants will get restaging scans every 2 cycles. Participants will continue to receive treatment ...

Phase

Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study

To date, CEUS criteria for non-invasive diagnosis of HCC include arterial phase hyperenhancement, followed by contrast washout in the portal venous or late phase. We would like to investigate the following points: whether arterial hyperenhancement alone is sufficient for the definite diagnosis of HCC in cirrhosis with CEUS whether a ...

Phase N/A

RadioEmbolization for the ADvancement of Y90 Glass Microspheres Registry

This study is a non-interventional, observational, prospective and global patient data registry. Approximately 1000 patients with liver cancers who are treated with TheraSpherewill be enrolled. Data regarding patient and treatment characteristics (TheraSphere and other anti-cancer treatments) will be collected within a 12 month period post TheraSphere administration to: Assess treatment ...

Phase N/A

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

This is a standard of care treatment guideline for high risk or relapsed solid tumors or CNS tumors consisting of a busulfan, melphalan, thiotepa conditioning (for solid tumors) or carboplatin and thiotepa conditioning (for CNS tumors) followed by an autologous peripheral blood stem cell transplant. For solid tumors, if appropriate, ...

Phase N/A

High Dose Rate Brachyablation of Primary Liver Lesions

Primary endpoints of this protocol are to demonstrate feasibility of an optimized, image-guided pre-planned workflow to deliver at least 25 Gy to the periphery of the target lesion while maintaining established dose constraints to normal tissues, and then to determine the maximum tolerated dose (MTD) of navigated percutaneous interstitial HDR ...

Phase

MRI Only Radiation Therapy With CPAP

The goal of this imaging study is to evaluate and improve the treatment planning techniques for abdominal radiation therapy. To accurately treat a tumor with radiation, Computed Tomography (CT) and Magnetic Resonance Images (MRI) are used to distinguish a tumor from normal, healthy tissue. However the quality of these images ...

Phase N/A

Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection

The purpose of this study is to learn whether patient-controlled epidural analgesia (PCEA) is a better method for managing pain after liver resection compared to patient-controlled analgesia (IV PCA). Currently, the standard pain control method for liver resection patients is IV PCA. There is not enough data on how epidural ...

Phase

Lung Dose in Patients Treated With Yttrium-90 for Hepatocellular Carcinoma

To calculate the delivered lung dose using quantitative volumetric analysis in a cohort of patients with unresectable hepatocellular carcinoma who undergo selective internal radiation therapy (SIRT) with Yttrium-90 glass microspheres (TheraSphere)-and compare this analysis to the lung dose estimated by established criteria. In addition, this study, will summarize the pre ...

Phase N/A

Proton Beam Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis

The standard treatment of advanced hepatocellular carcinoma (HCC) is sorafenib. Though the agent showed clear survival benefit in two randomized phase III trials, the benefit was modest and response rate was just a few percent. Therefore, other loco-regional modalities, like trans-arterial chemo-embolization (TACE), hepatic arterial infusion chemotherapy (HAIC), and radiotherapy ...

Phase N/A

Impact of Three-dimensional Visualization on Operation Strategy and Complications for Complex Hepatic Carcinoma

Because of the complexity of complex hepatic carcinoma,the limitations of 2D images of CT/MRI and the uncertainty of surgeons'experience, it is difficult for the surgeons to diagnosis and assess the operation strategy accurately based on traditional 2D imaging(CT/MRI).The aim of the multi-centre study is to evaluate correctly the impact of ...

Phase N/A