Search Medical Condition
Please enter condition
Please choose location

Oral Cavity Cancer Clinical Trials

A listing of Oral Cavity Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (24) clinical trials

Pembrolizumab in Combination With CRT for LA-SCCHN

Each subject will participate in the trial from the time the subject signs the Informed Consent Form (ICF) through the final protocol-specified contact. After a screening phase of 28 days, eligible subjects will receive treatment on Day -7 with a loading dose of the study drug. This will continue during ...

Phase

IRX-2 Regimen in Patients With Newly Diagnosed Stage III or IVA Squamous Cell Carcinoma of the Oral Cavity

This study will assess the activity and safety of the IRX Regimen in participants with newly diagnosed, untreated, surgically resectable squamous cell cancer of the oral cavity. Participants will be randomly assigned to receive either Regimen 1: IRX-2 + cyclophosphamide + indomethacin + zinc + omeprazole, or Regimen 2: cyclophosphamide ...

Phase

Validation of DNA Methylation Biomarkers for Oral Cancer Detection

In this study, investigators plan to recruit 40~50 patients who had, or currently has oral cancer. The study procedures are as below: - After the Informed Consent Form is signed, swab from the lesion site and normal site to obtain oral epithelial cells. - Collect tissue from the tumor site ...

Phase N/A

NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Patients With Locally Advanced Squamous Cell Carcinoma of the Oral Cavity or Oropharynx

Patients will receive a single administration of NBTXR3 on day 1, either as an intra-arterial or intratumor injection, followed by Intensity Modulated Radiation Therapy starting 24 hours later (day 2), and up to completion of 7 weeks, i.e. 70 Grays, 2Grays/fraction. Patients whose tumor has completely shrunk will be followed ...

Phase

Patient Evaluation for Head and Neck Surgery Branch Studies

This protocol will provide a means for screening potential candidates for head and neck surgery branch protocols. No investigational treatments will be administered in this protocol. The PI may, however, approve a patient who has been determined to be ineligible for HNSB protocols to undergo standard treatment because they present ...

Phase N/A

Fluorescence & Reflectance Imaging to Detect Oral Neoplasia

The Imaging Methods: All tissue and cells are made of tiny particles. Some of these particles give off small amounts of light. This light is called fluorescence. Researchers have learned that cancerous cells and normal cells give off different amounts and different types of fluorescence and also reflect light differently. ...

Phase N/A

Expression of Hypoxia-Inducible Factor- in Oral Precancers and Cancers

Expression of hypoxia-inducible factor-α in oral precancers and cancers

Phase N/A

Diagnosis of Oral Precancers and Cancers Using Optic Coherence Tomography

Diagnosis of oral precancers and cancers using optic coherence tomography

Phase

Expression of VEGF-C and VEGF-CR in Oral Cancers and Premalignant Lesions

The role of vascular endothelial growth factor-C (VEGF-C) and its receptors induced lymphangiogenesis and host inflammatory responses on the carcinogenesis of oral cancers and premalignant lesions

Phase N/A