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Chronic Fatigue Syndrome Clinical Trials

A listing of Chronic Fatigue Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (37) clinical trials

Open-Label Duloxetine Monotherapy in the Treatment of Posttraumatic Stress Disorder

Duloxetine has established efficacy for treatment of major depression, generalized anxiety disorder and diabetic peripheral neuropathic pain. Chronic PTSD is often treated with antidepressants, in fact there are only two FDA-approved treatments for PTSD. Yet many chronic PTSD patients, especially male combat veterans, have a limited response to antidepressant treatment ...


Prevention of Posttraumatic Stress Disorder (PTSD) With Early Hydrocortisone Treatment: Pilot

Posttraumatic stress disorder (PTSD) is the fourth most common psychiatric disorder and is estimated to affect more than ten million American children and adults at some point in their lives. Although a number of pre-, peri-, and acute phase post-trauma variables (e.g., prior trauma history, subjective life threat, injury) have ...

Phase N/A

Use of Sildenafil (Viagra) to Alter Fatigue Functional Status and Impaired Cerebral Blood Flow in Patients With CFS

Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients with Chronic Fatigue Syndrome.


The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure

Background: The clinical presentation of individuals with blast-related brain injury and post-traumatic stress reactions can be markedly similar and thus a clear description of the direct consequences of explosive blast is complicated by the emotional and cognitive sequelae of psychological trauma. The inability to clearly separate the basis of symptoms ...

Phase N/A

Treatment Effects of Narrative Exposure Therapy

In this study we want to compare Narrative Exposure Therapy (NET) to Waiting list controls. Adult patients with diagnosed Posttraumatic Stress Disorder following different types of trauma, will be included. Clinicians in psychiatric outpatient clinics will treat patients with NET, either immediately after assessment, or after a second assessment 3 ...


A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol

Background: Animal evidence indicates that some consolidated memories when reactivated (retrieved) need to be reconsolidated. During this process, memories can be enhanced or weakened. In a preliminary, randomized, double-blind, placebo-controlled study, we tested whether post-reactivation administration of the beta-adrenergic blocker propranolol, which reduces reconsolidation of aversive memories in rodents, would ...


Brain Injury Outcomes (BIO) Study

As of September 2015, 91 of the planned sample have been recruited and evaluated. Recruitment, enrollment, evaluation and re-evaluation is continuing.

Phase N/A

Telemental Health and Cognitive Processing Therapy

The proposed project is a 4-year prospective randomized clinical trial which conducts a direct comparison of the VTC and in-person modalities using rigorous methodology and a sophisticated analysis of equivalency between clinical and process outcome domains. In addition, cost effectiveness of this modality will be addressed. Approximately 126 combat Reservists, ...