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Kidney Cancer Clinical Trials

A listing of Kidney Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (23) clinical trials

Prospective Patient Reported Outcomes (PRO) Registry in Patients With Advanced Renal Cell Carcinoma

The PRO Kidney project will recruit a representative cohort of patients with advanced renal cell carcinoma (RCC) treated with systemic antiproliferative therapies such as TKIs, mTOR inhibitors, cytokines, antiVEGF or immune therapy. The aim of this study is to collect data on the effectiveness and patients´quality of life on preference ...

Phase N/A

Assessment of Bone Biomarkers for TKI Response in RCC With Bone Metastases HRQoL and Comparison of Imaging Techniques

Prospective observational study to assess: - Bone predictive biomarkers for tyrosine kinase inhibitor (TKI) response in renal cell carcinoma (RCC) patients with bone metastasis - Health Related Quality of Life (HRQoL) with TKI - Comparison of the sensitivity and specificity of whole body magnetic resonance versus bone scintigraphy and versus ...

Phase N/A

Study of Kidney Tumors in Younger Patients

PRIMARY OBJECTIVES: I. Classify patients with renal tumors by histological categorization, surgico-pathological stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies. (Loss of heterozygosity [LOH] testing discontinued as of April 2014) II. ...

Phase N/A

Effects of Monoclonal Antibody GC1008 in Blood Samples From Patients With Unresectable Locally Advanced or Metastatic Kidney Cancer or Malignant Melanoma Treated on Clinical Trial NCI-06-C-0200

OBJECTIVES: - To determine whether treatment with human anti-TGF-beta monoclonal antibody GC1008 results in a detectable decrease in phospho-Smad2 levels in freshly collected blood samples from patients with unresectable locally advanced or metastatic renal cell carcinoma or malignant melanoma treated on clinical trial NCI-06-C-0200. - To determine whether the decrease ...

Phase N/A

Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders

Background: - Disorders under investigation are: Autosomal dominant inherited urologic malignant disorders including: von Hippel- Lindau (VHL), hereditary papillary renal cancer (HPRC), Birt Hogg Dube (BHD) and hereditary leiomyomatosis and renal cell acarcinoma (HLRCC) as well as familial renal cancer. - Studies have led to the identification and characterization of ...

Phase N/A

Genetic Study of Patients With Inherited Urologic Malignancies

OBJECTIVES: - Characterize the natural and clinical histories of patients with inherited urologic malignancies. - Determine the genetic etiology of inherited urologic malignancies in which the gene defect is unknown, using linkage analysis, positional cloning, and evaluation of candidate genes. - Correlate specific mutations and associated protein domains with disease ...

Phase N/A

Collection of Blood Bone Marrow Tumor or Tissue Samples From Patients With Cancer to Study Drug Resistance

Background: Ongoing research in the Experimental and Molecular Therapeutics Sections, NCI, requires the availability of blood, serum, tumor, hair follicle and tissue samples from patients with cancer. Resistance is the underlying cause of treatment failure, and may present as acquired or intrinsic drug resistance. Patients with cancer frequently present with ...

Phase N/A

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

Background - Kidney, prostate, bladder, testis and penile cancer account for 22% of cancers diagnosed in the United States and are responsible for 10% of cancer deaths each year in the U.S. Understanding the genes and gene pathways that cause genitourinary malignancies will provide the foundation for the development of ...

Phase N/A

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Background - BHD is a rare, autosomal dominantly inherited disorder which confers susceptibility to develop multifocal, bilateral renal cancer, spontaneous pneumothorax and fibrofolliculomas. - BHD is caused by mutations in the BHD gene located on Chromosome17p11.2. - Defining the genetic and biochemical pathways leading to renal tumorigenesis in BHD may ...

Phase N/A