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Mastectomy Clinical Trials

A listing of Mastectomy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (8) clinical trials

Application Of Autologous Blood Products During Modified Radical Mastectomy

A frequent complication of mastectomy is seroma formation with rates in the literature reported at 3-50%. Although seroma formation can be considered more of a nuisance than a serious complication, the presence of seroma can lead to wound infection, skin flap necrosis, wound dehiscence, nerve injury, and lymphedema in mastectomy ...


Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

The purpose of this study is to compare using bupivacaine (a numbing medicine) along with the usual medications for post-operative pain control to using the usual medications for post-operative pain control alone. The addition of bupivacaine to the usual pain medications could better manage pain immediately after surgery. This study ...


Post Mastectomy Hypofractionated Radiotherapy in High Risk Breast Cancer

Eligible breast cancer patients with mastectomy and axillary dissection are divided into two groups: conventional fractionated (CF) radiotherapy of 50 Gray (GY) in 25 fractions within 5 weeks to ipsilateral chest wall and supraclavicular nodal region, and hypofractionated (HF) radiotherapy of 43.5 Gray (GY) in 15 fractions within 3 weeks ...


Pregabalin in Treating Pain in Women Undergoing Mastectomy or Lumpectomy

OBJECTIVES: Primary - To evaluate the effects of pregabalin on postoperative opioid requirements and opioid-related side effects in women undergoing mastectomy or lumpectomy. Secondary - To evaluate the effects of pregabalin on pain scores at 3 months after mastectomy or lumpectomy. OUTLINE: Patients are randomized to 1 of 2 treatment ...


Shave Margins vs. Standard Partial Mastectomy in Breast Cancer Patients

Some authors have investigated, in a retrospective fashion, the use of routine shave margins, where surgeons routinely take additional margins at the time of the initial partial mastectomy as a means of obtaining negative margins. While these retrospective studies have found that positive margin rates declined using this technique, opponents ...


Therapeutic Nipple Sparing Mastectomy.

This is a phase III, multicentric, single arm study with a sequential design using the exact conditional Poisson test. The primary objective of this prospective study is to evaluate whether selected breast carcinoma patients could be treated with nipple sparing mastectomy (NSM) with an acceptable low local recurrence rates. 450 ...


Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate TE Reconstruction

This double-blind, randomized, controlled clinical trial comparing patient-reported pain and pain medication/narcotic use between patients randomized to treatment (ropivacaine) or placebo (saline) delivered via paravertebral block to the mastectomy site. Candidates will have chosen to have a mastectomy on one side immediately followed with tissue expander placement breast reconstruction. Patients ...


Shandong Cancer Hospital Affiliated to Shandong University

In this study,the eligible breast cancer patients will be randomized divided into two groups. the study group receive the accelerated hypo-fractioned whole breast irradiation with a concurrent boost to the tumor bed (WBI 2.5Gy x18 and SIB 2.88Gy x18) and the control group receive conventional fractioned whole breast irradiation with ...