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Endometrial Cancer Clinical Trials

A listing of Endometrial Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (185) clinical trials

Benign Reproductive Tissue Analysis for Endometrial Cancer Markers

Our hypothesis is that silent molecular lesions, defined as molecular alterations detectable in histologically normal endometrial, ovarian, and tubal tissues, represent markers of cancer risk. Incessant ovulation represents one of the most widely-recognized models to explain the pathogenesis of ovarian cancer, with women who have had a high number of ...

Phase N/A

Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer

PRIMARY OBJECTIVES: I. To assess whether pelvic radiation therapy with concurrent cisplatin is more promising with respect to progression-free survival than pelvic radiation therapy alone in the treatment of recurrent uterine carcinoma limited to the pelvis and vagina. SECONDARY OBJECTIVES: I. To capture the sites of recurrence subsequent to treatment ...

Phase

Upper Vaginectomy Versus Brachytherapy in Patients With Early Stage Endometrial Cancer Treated With Laparoscopic Surgery

Women with ESEC scheduled for laparoscopic surgery will be enrolled and randomized in three arms [vaginectomy group (VG), brachytherapy group (BG), and control group (CG)]. All laparoscopic procedures will consist of total hysterectomy, bilateral salpingo-oophorectomy, peritoneal washing, systematic inspection of peritoneal cavity and biopsy of each suspect lesion, and pelvic ...

Phase

The Assessment of Preoperative Psychological Intervention on Stress in Women With Gynecological Malignancies

Surgery is considered one of the most stressful events in human life. Research indicates that patients show high levels of stress from at least six days before surgery and up to a week post the operation. Stress levels return to normalcy only after several weeks. Research shows that psychological interventions ...

Phase

Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia Oxford Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of endometrial cancer cases. - To define the proportion of endometrial cancer incidence attributable to mutations in known predisposing genes such as MSH2 and MLH1. - To determine the risk associated with these predisposing mutations by examining ...

Phase N/A

Longitudinal Evaluation of Women Undergoing Pelvic Exenteration for Treatment of Gynecologic Malignancy

Prospective Study Procedures: Study Procedures: If you agree to take part in this study, you will be asked to complete a series of questionnaires at specific times. The questionnaires ask questions about how you feel, what you are able to do, depression, coping, social support, sexual function, and your body ...

Phase N/A

DOvEEgene: Developing and Validating a Novel Molecular Screening Test for the Early Diagnosis of Cancer of the Endometrium Tubes and Ovaries

The vast majority of deaths from ovarian cancer are from the high-grade serous cancer (HGSC) subtypes. The currently available tests for ovarian cancer diagnosis such as, blood tumour marker CA-125 and transvaginal ultrasound scan of the ovaries, have poor sensitivity and specificity therefore are not suitable for diagnosing early disease. ...

Phase N/A

A Pilot Study to Determine the Efficacy of Fluorescein Visualization of the Uterus in Detecting Endometrial Cancer Invasion

To determine if Fluorescein systemic injection during hysterectomy procedure can be useful in revealing the depth of endometrial cancer invasion.

Phase N/A

Sentinel Lymph Node Detection in Endometrial Cancer

Endometrial cancer is an increasingly common gynecologic malignancy. The cumulative 5-year survival rate for node negative patients is 94%, 75% in those with metastatic pelvic lymph nodes only and 38% in patients with pelvic and paraaortic metastases. The proportion of node positive patients in adequately staged patient materials (usually high ...

Phase N/A