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Endometrial Cancer Clinical Trials

A listing of Endometrial Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (134) clinical trials

People with ovarian cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

The purpose of this research study is to determine if pelvic floor therapy is effective in treating pain related sexual dysfunction. We are interested in examining pelvic floor therapy (a type of gynecologic physical therapy) as an intervention for sexual dysfunction.

Phase N/A

Effect of a Lifestyle Intervention on Nutritional Status and Prognosis of Endometrial Cancer Survivors

Endometrial cancer (EC) is the fifth most commonly diagnosed malignant neoplasm among women worldwide. The incidence of EC is higher in high-income countries, but it has been increasing in low- and middle-income countries. The main risk factors for EC include the presence of comorbidities, such as diabetes mellitus and hypertension, ...

Phase N/A

The Role of Hypoxia as a Selective Pressure for TP53 Mutations

Cancer tissue harbours a multitude of genetic alterations, and it is well-established that when certain key alterations develop, they are powerful determinants of tumour behaviour (growth rate, potential to spread). One of the most sinister and well-recognized alterations is in a gene called TP53. Another feature of tumours that results ...

Phase N/A

Use of the Sentinel Node Biopsy for Early Endometrial Cancer.

All the sentinel node biopsy procedures for endometrial cancer will be record online via the REDCap tools, securized on a servor in Saint-Luc. Automatic email for the following of the patients and the post operative event will be send regularly for every patient to the physicians who include the patient. ...

Phase N/A

Assisted Exercise in Obese Endometrial Cancer Patients

Primary Objective: To evaluate changes in body weight, fitness, bi-manual dexterity, exercise motivation and self-reported eating behavior (via questionnaires) before and after a 16-week exercise intervention (EOT) and 12 and 24 weeks post-EOT, in obese EC patients who will be randomized to perform 'assisted' or voluntary exercise. Secondary Objectives: Objective ...

Phase N/A

Identification and Characterization of Endometrial Cancer With Specific Tumor Markers in Serum and Endometrial Tissue

List of abbreviations: HE4: Human Epididymis Protein 4 CA125: Carbohydrate Antigen 125 Ki67: antigen KI67 EC: Endometrial Cancer CT: Computed Tomography NMR: Nuclear Magnetic Resonance FIGO: International Federation of Gynecology and Obstetrics The purpose of this study is: The proportion of positive H-score of HE4, as quantified in endometrial tissue. ...

Phase N/A

Durvalumab Tremelimumab + Radiotherapy in Gynecologic Cancer

This research study is a Phase I clinical trial, which tests the safety of an investigational drug or drugs and also tries to define the appropriate dose and combination of the investigational drugs to use for further studies. "Investigational" means that the drugs are being studied but have not been ...

Phase

Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

Primary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. Second end points: To analyze the appearances of side-effects.

Phase

Improving the Treatment for Women With Early Stage Cancer of the Uterus

Currently the standard treatment for early stage endometrial cancer or endometrial hyperplasia with atypia is a total hysterectomy (an operation to remove the uterus) and removal of both ovaries. While highly effective, this surgery carries significant side effects for: young women who still wish to have children and would lose ...

Phase