Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Musculoskeletal

Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters
 

Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (91) clinical trials

Post-market Registry Study on the Physica System Total Knee Replacement

This is a post-market registry study; the study device is FDA cleared and used according to the intended use. This is a multi-centre, prospective, non-randomized study. Subjects will be implanted with one of the following configurations of the Physica system: Physica KR (Kinematic Retaining), Physica CR (Cruciate Retaining) or Physica ...

Phase N/A

Hypnosis for Symptom Management in Elective Orthopedic Surgery

Patients will be recruited by through orthopedic surgery clinics or contacted by after pre-screening via chart review and given an information brochure. If they are interested in the trial will be emailed or given a paper copy of the consent form and scheduled for a single additional visit in the ...

Phase N/A

iCORE: Collaborative Orthopedics Outcomes Registry

The goal of this registry is to review the data collected and research ways to improve patient safety, quality of care, and medical decision-making, reduce medical spending, and help advance orthopedic science and bioengineering.

Phase N/A

Unicondylar- or Total Knee Replacement? Patient Satisfaction Function and Muscle Mass

Objective: The investigators aim with the present study was to compare patient related outcome measurements, knee function and muscle mass in patients operated with an UKR or a TKR for medial gonarthritis. Hypothesis: The investigators hypothesize that a greater number of patients might benefit from a less invasive surgery in ...

Phase N/A

Effects of Computer Navigation Versus Conventional Total Knee Arthroplasty on Endothelial Damage Marker Levels

Total knee arthroplasty (TKA) is one of the most successful surgery in orthopaedic field. However, occasional outliner from perfect alignment after prosthesis implantation and unavoidable complications are still concerns. The usage of navigation-assisted system on total knee arthroplasty has provided better accuracy of the component alignment and quantity in knee ...

Phase N/A

Comparison of Three Knee Replacements

The study will compare the short-term functional outcome (at 2 years) of TKR performed with a novel TKR design (Persona , Zimmer, Warsaw, IN, USA) against TKRs performed with two conventional designs (PFC, DePuy, Warsaw, IN, USA and Nexgen, Zimmer, Warsaw, IN, USA).

Phase N/A

Physica KR Fluoroscopy Study

The aim of this study is to assess the in vivo kinematics and range of motion of a single-surgeon clinical series of TKA performed with a fixed-bearing cruciate retaining total knee arthroplasty that has a roll-back mechanism and compare it with the kinematic of the normal healthy knee. Patients would ...

Phase N/A

Signature Personalised Patient Care System With the Vanguard Knee System Study

The purpose of this study is to determine whether the percentage cases which have ideal mechanical axial alignment using the Vanguard total Knee implant with the Signature cutting blocks is higher than those without the use of Signature when measured immediately post-operatively. Other outcomes will include knee assessments and patient ...

Phase N/A

An Intravenous Iron Based Protocol for Preoperative Anaemia in Hip and Knee Surgery - An Observational Study

Patients presenting with preoperative anaemia prior to hip and knee arthroplasty has a high risk of receiving allogeneic blood transfusion and anaemia has been associated with increased postoperative morbidity and mortality. While IV-iron administration may raise Hb prior to surgery, existing guidelines for addressing and treating preoperative anaemia is not ...

Phase N/A

The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement

Patients undergoing total knee arthroplasty will be randomized into two groups: control and placebo. Eache patient will undergo total knee arthroplasty under general anesthesia. Both groups will get the same anesthetic protocal. At the end of surgery, before awakening patients will recieve either a nitroglycerin or placebo patch on their ...

Phase N/A