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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (90) clinical trials

Fit-Joint: Getting Fit for Hip or Knee Replacement

Study Design: The proposed study is a pilot randomized controlled trial comparing a pre-operative multi-modal intervention and standard care among pre-frail/frail patients undergoing total hip or knee replacement surgery. Pre-frail (score of 1 or 2) or frail (score of 3-5; Fried Frailty Phenotype) patients, 60 years undergoing elective unilateral total ...

Phase N/A

Clinical Study Evaluating the Outcomes of a New Knee System With a Physiological Rollback Mechanism

The aim of this study is to assess the clinical, radiographic and patient-reported outcome measures (PROMs) after total knee replacement with Physica KR, define the survivorship of the implants and identify possible risk factors that may lead to failure.

Phase N/A

The Influence of Rapid Recovery on Sleep Quality Following Total Knee Replacement Surgery

The purpose of this study is to evaluate the influence of rapid recovery on sleep quality following total knee replacement surgery.

Phase N/A

Adductor Canal Block Versus Lumbar Plexus Block for Post Operative Pain Management After Total Knee Replacement

This prospective double-blinded randomized controlled trial is comparing ultrasound guided adductor canal block (ACB) versus ultrasound-guided lumbar plexus block (LPB) in patients undergoing total knee arthroplasty aiming at decreasing post-operative pain, helping in early mobilization and better physiotherapy. This study hypothesizes that ACB, compared with LPB, will exhibit less motor, ...

Phase N/A

In-home Versus Hospital Preoperative Training for Patients Undergoing Total Knee Replacement

In this work the importance of the potentiation and recovery of the balance with a physiotherapeutic intervention that begins in the early preoperative phase is compared with the conventional postoperative rehabilitation. The objective is to evaluate the influence of a muscle enhancement protocol in which a specific work of balance ...

Phase N/A

Pre-operative Radiological Measurement to Assess Femur Rotational Alignment

Purpose: This study outlines the benefits of the proximal tibia angle (PTA) in evaluation of the pre-operative individual condylar twist angle (CTA) in total knee arthroplasty. Methods: Condylar twist angle and proximal tibia angle were obtained from 33 female healthy participants using computed tomography (CT). The CTA, angle between clinical ...

Phase N/A

Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study

This is a pilot study that will look at how pain management will be effected when pharmacogenomic testing is utilized to select and dose narcotic pain medications prescribed for breakthrough pain in post-operative total knee arthroplasty (TKA) patients. Patients will receive individualized analgesics and doses for pain mitigation based on ...

Phase N/A

RSA and Clinical Comparison of Anatomical and Mechanical Alignment in Total Knee Replacement

Problem to be addressed Knee osteoarthritis is a degenerative joint disease that is very prevalent in the general population and can cause significant functional impairment. Total knee arthroplasty (TKA) is the definitive treatment of choice, but rarely accomplishes complete restoration of natural knee biomechanics. Various factors may influence post-operative function: ...

Phase N/A

Biomechanical Assessment of a High Congruency Knee Bearing

This is a double blind randomised controlled trial. The aim of the study is to compare the biomechanical performance of knee replacements with different bearing designs to that of a native or natural knee. The hypothesis is that a mobile bearing design with a high congruency bearing will allow the ...

Phase N/A

Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.

Knee pain and stiffness is a common problem which can sometimes be improved by inserting a replacement knee joint. An anaesthetist is a doctor who specialises in looking after patients undergoing surgery, and there are a variety of different anaesthetics which can be used for knee replacement surgery. These include ...

Phase N/A