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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (91) clinical trials

The Influence of Rapid Recovery on Sleep Quality Following Total Knee Replacement Surgery

The purpose of this study is to evaluate the influence of rapid recovery on sleep quality following total knee replacement surgery.

Phase N/A

Adductor Canal Block Versus Lumbar Plexus Block for Post Operative Pain Management After Total Knee Replacement

This prospective double-blinded randomized controlled trial is comparing ultrasound guided adductor canal block (ACB) versus ultrasound-guided lumbar plexus block (LPB) in patients undergoing total knee arthroplasty aiming at decreasing post-operative pain, helping in early mobilization and better physiotherapy. This study hypothesizes that ACB, compared with LPB, will exhibit less motor, ...

Phase N/A

In-home Versus Hospital Preoperative Training for Patients Undergoing Total Knee Replacement

In this work the importance of the potentiation and recovery of the balance with a physiotherapeutic intervention that begins in the early preoperative phase is compared with the conventional postoperative rehabilitation. The objective is to evaluate the influence of a muscle enhancement protocol in which a specific work of balance ...

Phase N/A

Pre-operative Radiological Measurement to Assess Femur Rotational Alignment

Purpose: This study outlines the benefits of the proximal tibia angle (PTA) in evaluation of the pre-operative individual condylar twist angle (CTA) in total knee arthroplasty. Methods: Condylar twist angle and proximal tibia angle were obtained from 33 female healthy participants using computed tomography (CT). The CTA, angle between clinical ...

Phase N/A

Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study

This is a pilot study that will look at how pain management will be effected when pharmacogenomic testing is utilized to select and dose narcotic pain medications prescribed for breakthrough pain in post-operative total knee arthroplasty (TKA) patients. Patients will receive individualized analgesics and doses for pain mitigation based on ...

Phase N/A

Biomechanical Assessment of a High Congruency Knee Bearing

This is a double blind randomised controlled trial. The aim of the study is to compare the biomechanical performance of knee replacements with different bearing designs to that of a native or natural knee. The hypothesis is that a mobile bearing design with a high congruency bearing will allow the ...

Phase N/A

Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.

Knee pain and stiffness is a common problem which can sometimes be improved by inserting a replacement knee joint. An anaesthetist is a doctor who specialises in looking after patients undergoing surgery, and there are a variety of different anaesthetics which can be used for knee replacement surgery. These include ...

Phase N/A

All Polyethylene Versus Metal Backed Tibial Components in Knee Replacement

Summary of design and methodology. When a patient who is appropriate for the study is added to the waiting list for a Total Knee replacement they will be given (or if missed, posted) an information sheet about the study. This will allow patients several weeks to read the information and ...

Phase N/A

Kinematic Analysis: Posterior Stabilized Fixed Bearing Total Knee Arthroplasty With Attune Knee System - Phase 2

A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal knee. Specifically, posterior stabilizing (PS) knees have been found to be associated with lower amounts of posterior ...

Phase N/A

Audiovisual Distraction for Patients Undergoing Total Knee or Hip Replacement Surgery

The perioperative period is often anxiety-provoking experience for many of our patients. Pain and awareness are the two primary concerns voiced most frequently. For total knee and hip replacement surgery, we offer our patients a spinal anesthetic which produces complete sensory blockade below the level of the waist. Despite a ...

Phase N/A