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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (125) clinical trials

Non-Interventional Consecutive and Prospective Study of e.Motion PS Pro Prosthesis in the Total Knee Artroplasty

This post-market clinical follow-up study intends to investigate the survival rate at 5 years of the e.motion PS Pro System.

Phase N/A

Outcomes of Injections in Patients Waiting for Total Knee Replacement

The objective of this research is to evaluate the short-term results of viscosupplementation in patients with advanced osteoarthritis of the knee. There is a bigger demand of patients requiring total knee arthroplasty than the number of surgeries performed by the Unified Health System in Brazil. For this reason the queues ...

Phase

The Effect of Dexamethasone on Pain After Total Knee Replacement Surgery

The purpose of this study is to examine, if a single-dose of dexamethasone given during the operation, alleviates pain after knee replacement surgery. This is also a dose-finding study comparing two doses of dexamethasone. Total knee arthroplasty causes considerable pain. Multimodal analgesia and peripheral nerve blocks are used for treatment ...

Phase

Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty

Following ethics approval by the Ospedale San Raffaele, 142 adults aged between 45 and 80 years old will be recruited for the study, excluding people with unstable serious disease (e.g., heart or lung disease), previous orthopedics pathologies on the same side (e.g., hip arthroprosthesis), pregnancy and intake of psychotropic drugs. ...

Phase

Making Sense Out of Total Knee Sensor Assisted Technology: A Randomized Control Trial

This study will compare a group of total knee arthroplasty patients who receive sensor guidance technology for soft tissue balancing intra operatively to a group of patients who receive surgeon guided soft tissue balancing. Patients will be randomized to either the experimental group with the sensor guided technology or the ...

Phase N/A

A PROMs Based Educational Tool (PROM-DA) for Patients Considering Total Knee Arthroplasty

The primary objectives of this study are to: 1) develop an educational tool known as the Patient Reported Outcome Measure informed Decision Aid (PROM-DA) that will describe the options for patients considering total knee arthroplasty (TKA) surgery, and help them imagine what to expect if they choose either option; 2) ...

Phase N/A

Understanding GMK Sphere Implant Tibiofemoral Kinematics by Means of Dynamic Videofluoroscopy

The objective of this research project is to perform a comparative study on the in vivo kinematics of the GMK Sphere prosthesis in comparison to the conventional GMK PS Fixed Bearing TKA and the GMK UC Fixed Bearing TKA.

Phase N/A

Antibiotic Prophylaxis in Primary Joint Arthroplasty of the Hip and Knee.

In phase 1 of this study all Dutch hospitals and clinics performing hip and/or knee arthroplasty will be contacted to supply data concerning type and duration of antibiotic prophylaxis. The investigators will also ask whether debridement with implant retention for early infection is registered in the LROI. The investigators will ...

Phase N/A

A Comparison of Analgesic Efficacy of Ultrasound-Guided Genicular Nerve Block Versus Saline Injection for Total Knee Replacement

Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee analgesia for patients recovering from total knee replacement surgery compared to saline injection? Hypotheses The investigators hypothesize that the combination of ultrasound-guided adductor canal block (ACB) and genicular nerve block will achieve lower opioid consumption and therefore lead to ...

Phase

Tourniquet Application on Total Knee Arthroplasty

Sixty participants undergoing unilateral TKA would be recruited in this study. On one side, the tourniquet would be inflated immediately before incision and deflated after the use of the cement , and 10 minutes later(after the hardening of the cement) , reinflate the tourniquet and deflate at the end of ...

Phase N/A