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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (95) clinical trials

Optimizing Physical Activity Outcomes After Total Knee Arthroplasty

This randomized clinical trial will assess the efficacy of using physical activity behavior change intervention for Veterans recovering from total knee arthroplasty. Testing will occur at baseline (before surgery), at intervention midpoint (8 weeks after surgery), end of intervention (14 weeks after surgery), and 24 weeks after intervention. The primary ...

Phase N/A

Unity Total Knee Replacement Using Two Different Surgical Techniques

This study will be conducted at a single centre. The study has two treatment groups. One group of 50 knees (approximately 50 subjects) will have a surgical method that uses mechanical alignment (alignment based on how the leg and knee joint move) to determine the proper position of the knee ...

Phase N/A

Triathlon Partial Knee Replacement (PKR) Outcomes Study

The purpose of the study is to evaluate the Triathlon PKR Knee System and determine whether or not the success rate of this device is no worse than the reported success rate of similar devices.

Phase N/A

Study of Peri-Articular Anaesthetic for Replacement of the Knee

The trial design is a patient-blinded multi-centre, active comparator, randomised controlled two-arm parallel group superiority trial of liposomal bupivacaine plus bupivacaine hydrochloride versus bupivacaine alone for post-operative pain in patients undergoing knee replacement surgery. Patients will be randomised in a 1:1 ratio. The randomised controlled trial (RCT) design is robust ...

Phase

Movement Pattern Biofeedback Training After Total Knee Arthroplasty

Currently in the United States, more than 700,000 total knee arthroplasty (TKA) surgeries are performed annually, with projections of 3.5 million performed annually by 2030. The increasing incidence of TKA comes with an immediate need for establishing optimal rehabilitation guidelines to remediate common post-TKA physical impairments and improve functional outcomes. ...

Phase N/A

JOURNEY II XR Safety and Effectiveness PMCF

Total knee arthroplasty (TKA) is considered the most beneficial and cost-effective treatment for end-stage knee arthritis and is the most frequently performed joint replacement surgery. TKA is also indicated for earlier osteoarthritis (OA) interventions, such as osteotomy or unicompartmental replacement, when additional treatment is warranted. One device option available once ...

Phase N/A

Ten Year Implant Survivorship of the ANTHEM Total Knee System

The ANTHEM Study is a prospective, multicentre, cohort study to collect relevant patient reported, clinical, surgical and radiological data from 196 subjects implanted with the ANTHEM Knee System for degenerative joint disease in up to 6 clinical sites globally. Total study duration for study participants will be 10 years with ...

Phase N/A

Pre-operative Intravenous Steroid in Total Knee Replacement for Pain Relief and Recovery

Osteoarthritis of the knee is a common and important disease in the population. As a joint replacement centre, around 600 total knee replacements were performed in Queen Elizabeth Hospital and Buddhist Hospital per year. Despite multiple anesthetic methods and analgesics protocols, post-operative pain remains a significant problem. Perioperative use of ...

Phase

Effect of Suction Drains in Total Knee Arthroplasty With Tranexamic Acid

Problem Suction drains during TKA present certain costs to the health system and requires additional nursing care. There is no clear evidence that supports their use, and no studies so far have compared blood loss in patients with or without drains when TA is administered during TKA. Hypothesis During total ...

Phase N/A

Analgesic Effect of Adding an Adductor Canal Block to a Femoral Triangle Block for Total Knee Replacement

The aim of the study is to investigate whether the addition of an adductor canal block to a femoral triangle block will provide better analgesia for patients after total knee replacements.

Phase