Search Medical Condition
Please enter condition
Please choose location
Clear Trial Filters

Polycystic Ovarian Syndrome Clinical Trials

A listing of Polycystic Ovarian Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (74) clinical trials

Investigation of Estradiol-induced Gonadotropin Surge Generation in PCOS

LH and FSH are hormones made by the pituitary gland. The pituitary is a small gland located below the brain. LH and FSH control the ovaries, including ovarian follicle (egg) development and ovarian hormone production. Estradiol is a hormone that mostly comes from the ovaries. In particular, as an ovarian ...


Vitamin D Treatment Pharmacogenetics and Glucose Metabolism

Background: Polycystic ovary syndrome (PCOS) is as common as 5-10% of all women in Austria. PCOS women frequently present with metabolic disturbances, hyperandrogenism and infertility. New therapy concepts are warranted. In our recent pilot study, vitamin D (vitD) supplementation significantly improved glucose metabolism and fertility. However, the efficacy of vitD ...


Metformin in Infertile PCOS Patients

Infertile PCOS patients having three ovulatory cycles under metformin, administered using tailored protocol, will be enrolled and randomized in two groups (groups A and B). Patients of group A will continue metformin administration for further three cycles followed by six months of progestogens cyclically administered, whereas patients of group B ...


CCRC: The Effects of Walnuts Walnut-Oil Almonds and Fish Oils on Glucose Homeostasis in Polycystic Ovary Syndrome (PCOS)

Polycystic ovary syndrome is a common disease that affects 1 out of 16 women. Metabolic and endocrine abnormalities seen in PCOS include insulin resistance, androgen excess and infertility. This study focuses on the insulin resistance aspect because increased insulin resistance leads to premature onset of impaired glucose tolerance or diabetes ...

Phase N/A

Determining How Quickly Progesterone Slows LH Pulse Frequency

Studies under this protocol will be performed in normally cycling women and in women with PCOS from 18 to 35 years old. Criteria for PCOS will be (a) clinical and/or biochemical evidence of hyperandrogenism, (b) oligomenorrhea, and (b) the absence of clinical or biochemical evidence of other potential causes of ...


Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)

There will be 2 groups of treatment; each group will consist of 62 subjects with the treatment regimens : Treatment I : 1 capsule of DLBS3233 100 mg (once daily) and 1 placebo caplet of Metformin XR (twice daily) Treatment II : 1 caplet of Metformin XR 750 mg (twice ...


Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome

The purpose of the study is to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.


Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOS

In women with polycystic ovary syndrome (PCOS) androgen excess is fundamental to the clinical and physiological alterations of this disorder. In particular, androgen overproduction induces distinctive PCO morphology and appears to influence follicle function. Studies conducted in animals and nonhuman primates have demonstrated that androgens increase follicle number and in ...


Metformin Vitamin D and Depression in Polycystic Ovary Syndrome (PCOS) Trial

This is a single center, open-label, randomized, pilot clinical trial. Women with polycystic ovary syndrome and depressed mood, who are insulin resistant and vitamin D insufficient are eligible. Subjects are randomly assigned to one of two interventions: Vitamin D versus metformin. Subjects are followed with questionnaires and a final wrap-up ...


The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome

The patients with PCOS will be recruited to receive folic acid (45 patients) and equal number will receive no folic acid