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Polycystic Ovarian Syndrome Clinical Trials

A listing of Polycystic Ovarian Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (102) clinical trials

Is There Association Between Vitamin D Levels And Insulin Resistance In Polycystic Ovary Syndrome?

Polycystic ovary syndrome (PCOS) is the most common gynecological endocrinopathy among women of reproductive age. The prevalence of PCOS among such women is estimated to be 6.4% to 6.8% worldwide. PCOS is a heterogeneous androgen excess disorder with different degrees of reproductive and metabolic dysfunctions. There are many considerations to ...

Phase N/A

Does Vitamin D Break the Vicious Circle of Polycystic Ovarian Syndrome of Insuline Resistance ?

Research question: In PCOS patients, is there any effect of vitamin D supplementation therapy on plasma concentrations of adipokines (ghrelin, resistin and adiponectin), follistatin and activins? Research hypothesis: There is a significant effect of vitamin D supplementation therapy on plasma concentrations of adipokines (ghrelin, resistin and adiponectin), follistatin and activin.


Hyperandrogenemia and Altered Day-night LH Pulse Patterns

Late pubertal obese girls with hyperandrogenemia have altered day-night patterns of LH secretion when compared to those without hyperandrogenemia. In addition, a previous study revealed that late pubertal adolescents with hyperandrogenemia demonstrate impaired suppression of LH pulse frequency with estradiol and progesterone administration for one week. This study will address ...


The Impact of Obstructive Sleep Apnoea in Women With Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. PCOS is associated with multiple co-morbidities including obesity, insulin resistance, subfertility, impaired quality of life (QoL) and increased risk of type 2 diabetes. Obstructive sleep apnoea (OSA) is a common medical condition that is often ...

Phase N/A

Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction

BACKGROUND Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive age women with a prevalence as high as 15% using Rotterdam diagnostic criteria.1 PCOS is a heterogeneous clinical disorder characterized primarily by chronic anovulation and hyperandrogenism.2 A number of other metabolic and health complications are associated with ...

Phase N/A

Letrozole Versus Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome

Polycystic ovary syndrome is the major cause of anovulatory infertility. Clomiphene citrate is the most commonly used oral agent for ovulation induction in this group, but there are some drawbacks with the use of it.


N-Acetylcysteine and L-carnitine in Pcos

N-Acetylcysteine was compared to L-carnitine in clomiphene citrate in Pcos women to detect the hormonal and metabolic effect


Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome

Evidence from initial analysis of 5 SNPs in the one-carbon metabolism pathway suggests that one-carbon pathway genes may predict risk of ocular changes and possible vision impairment during and after long-duration space flight. It is not precisely known whether it is these particular genes, or a haplotype of genes that ...

Phase N/A

MicroRNA as Biomarkers for Development of Metabolic Syndrome in Women With Polycystic Ovary Syndrome

The study consist of 2 parts: A cross-sectional study of a cohort of women with PCOS with analysis of materials from the established biobank. (the PICOLO cohort) Data and blood samples from 266 women with PCOS was collected from January 2010 - February 2013 as a part of the PICOLO ...

Phase N/A

Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome

The purpose of the study is to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.