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Polycystic Ovarian Syndrome Clinical Trials

A listing of Polycystic Ovarian Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (74) clinical trials

Polycystic Ovary Syndrome and Exercise

Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder characterized by oligo-ovulatory menstrual dysfunction, androgen excess and polycystic ovaries. It affects ten to fifteen percent of reproductive-age women and has been associated with complications in reproductive, metabolic and cardiovascular health. Current Clinical Practice Guidelines suggest exercise and weight loss for ...

Phase N/A

PCOS Treatment Using DLBS3233 Metformin and Combination of Both

There will be 3 groups of treatment (N = 186), each consist of 62 subjects, as the following: Treatment I : DLBS3233 100 mg once daily Treatment II : Metformin XR 750 mg twice daily Treatment III : DLBS3233 100 mg once daily and Metformin XR 750 mg twice daily. ...

Phase

Chromium in Patients With Polycystic Ovary Syndrome Undergoing Intracytoplasmatic Sperm Injection (ICSI)

This study is a prospective, double-blind, randomized controlled trial . Ethical committee approval is obtained. The study includes infertile obese patients with PCOS diagnosed according to Rotterdam criteria, who are scheduled for ICSI cycle. Patients with body mass index (BMI) 30-35kg/m2 are included. Women with diabetes, thyroid disorder or other ...

Phase N/A

Androgen Excess as a Mechanism for Adipogenic Dysfunction in PCOS Women

Aim 1. Compare differences in SC abdominal adipogenesis of lean PCOS women vs. age- and BMI-matched controls Subjects and clinical assessment: We will recruit 36 lean (18.5-25 kg/M2) PCOS subjects and 12 age- and BMI-matched controls. Subjects will complete a standardized questionnaire emphasizing menstrual dating, abnormal hair growth and acne. ...

Phase

Androgen Responses to hCG and Ovarian Morphology in PCOS

50-100 PCOS and 50-100 normal women matched for age (<37 yr) and BMI (<35) will be studied. PCOS and normal women in the mid-follicular phase (day 5-7) of the menstrual cycle will receive an iv injection of hCG as previously described (see Experimental Design). Basal and stimulated blood samples will ...

Phase N/A

Clinical Sciences Research Proposal- The Effect of Physical Exercise on PCOS Overweight Female Adolescents

30 teenage and young adult females, aged 10-25 years old. The minimum hormonal age for inclusion is menarche. Overweight- with a Body Mass Index (BMI) percentage above 85%, divided into 2 groups: 15 girls with diagnosed PCOS, and 15 girls without diagnosed PCOS, without any other medical comorbidities. Followed at ...

Phase N/A

Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome

The primary aim of this trial is to investigate adipose tissue function in women with and without polycystic ovary syndrome (PCOS). PCOS is a common endocrine disorder in young women. The pathogenesis behind PCOS is complex and only partly understood, and deeper mechanistic insight is needed. Insulin resistance is a ...

Phase N/A

DAPA EQW DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)

Polycystic ovary syndrome is a heterogeneous condition characterized by disordered reproductive and metabolic function which accounts for the myriad of clinical features including androgen excess, chronic anovulation, insulin resistance adiposity, and dyslipidemia. This syndrome is highly prevalent, affecting between 8 and 18% of the female population, depending on the diagnostic ...

Phase

Improving Reproductive Function in Women With Polycystic Ovary Syndrome by High Intensity Interval Training

The aim is to investigate whether 16 weeks of high intensity interval training, followed by 36 weeks of home-based exercise, will improve menstrual frequency in women with Polycystic Ovary Syndrome (PCOS) compared with a non-exercising control group.

Phase N/A

The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

Groups Experimental treatment: Metformin-GLP-1 Receptor Agonist Therapy. Regular treatment: Metformin-Oral Contraceptive(OC) Therapy. Time Point: Initial treatment; Post-treatment (4w); Post-treatment (8w); Post-treatment (12w); Assess reproductive functions and cardiovascular risk factors.

Phase