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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (15) clinical trials

This is a Phase II, randomised, multi-centre, double-blind, placebo-controlled proof-of-concept study to assess the safety, tolerability and efficacy of oral Xanamem™ once daily in adult subjects with mild dementia due to AD.

Phase

The rrAD study is testing several strategies that may reduce the risk of Alzheimer’s disease in individuals at risk for the disease when compared to usual care. These strategies include: Aerobic exercise Intensive medical management of blood pressure and cholesterol The combination of these two approaches

Phase

Clinical Trial of Ultra-high Dose Methylcobalamin for ALS

To examine the clinial efficacy and safety of ultra-high dose (50mg, im, twice a week) methylcobalamin in retarding the progression of symptoms in amyotrophic lateral sclerosis (ALS) patinets, we enroll ALS patients diagnosed by revised-Awaji-El Escorial criteria within 12 months after the clinical onset. First they are followed for 12 ...

Phase

A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia

The purpose of this study is to test the feasibility and efficacy of a 10-week multi-dimensional intervention for older adults with subjective cognitive concerns (SCC). The goal of this intervention is to enhance compensation skills related to everyday executive and everyday memory functions through training in the systematic use of ...

Phase N/A

Advanced Dementia and End-of-life

Two visits at home or in the residential geriatric care at intervals of eight to twelve weeks are scheduled. The following data is collected at enrollment: Informed consent of the caregiver and of the patient or rather the caregiver with powers of attorney Sociodemographic data (caregiver and person with dementia), ...

Phase N/A

Dementia Symptom Management at Home Program

Alzheimer's Disease and Related Disorders (dementia) poses a significant challenge to our public health. While many persons with dementia are cared for by friends and family in the community with the assistance of home healthcare, most home healthcare clinicians and agencies are ill prepared to care for this population and ...

Phase N/A

A Trial to Evaluate the Safety Efficacy and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type

This is a phase 3, 12-week, multicenter, randomized, double-blind, placebo-controlled, fixed-dose trial designed to assess the efficacy, safety, and tolerability of brexpiprazole compared with placebo. The trial consists of a 12-week double-blind treatment period with a 30 day follow-up. The trial population will include male and female subjects between 55 ...

Phase

Longitudinal Early-onset Alzheimer's Disease Study Protocol

The LEADS study is a non-randomized, natural history, non-treatment study. Enrolled participants must be 40 - 26 (inclusive) years of age, with MCI due to AD or probable AD (EOAD) or have no significant memory impairment (CN). Approximately 400 EOAD participants and 100 CN participants will be enrolled at approximately ...

Phase N/A

Phase 1 Test-retest Evaluation of [18F]MNI-958 PET

The overall goal of this protocol is to evaluate [18F]MNI-958 also known as APN-0000455 or PM-PBB3, a tau targeted radiopharmaceutical. The specific objectives are: To measure the dynamic uptake and washout of [18F]MNI- 958 in brain using positron emission tomography (PET) in patients with Alzheimer's disease, Progressive Supranuclear Palsy and ...

Phase

Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain

The overall goal of this imaging trial is to evaluate [18F]PI-2620, a tau targeted positron emission computed tomography radioligand, in individuals with tauopathies and healthy volunteers (HV).

Phase N/A