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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (9) clinical trials

This is a Phase II, randomised, multi-centre, double-blind, placebo-controlled proof-of-concept study to assess the safety, tolerability and efficacy of oral Xanamem™ once daily in adult subjects with mild dementia due to AD.


The rrAD study is testing several strategies that may reduce the risk of Alzheimer’s disease in individuals at risk for the disease when compared to usual care. These strategies include: Aerobic exercise Intensive medical management of blood pressure and cholesterol The combination of these two approaches


11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes

Study design: Multi-center, Five-arm Subjects Patients with PD without dementia; Patients with PD with mild cognitive impairment (MCI); Patients with PD with dementia; Patients with a dementia with Lewy bodies(DLB); Healthy person Sample size: 200, including a PD without dementia group of 75 patients, a PD with MCI group of ...


In-Home Care for Patients With PSP and Related Disorders

Participants can elect to complete either the Home Visit Arm of the study or the Usual Care Arm of the study. Home Visit Arm: This interdisciplinary home visit program consists of 4 visits to patients' homes over the course of one year from a team of a movement disorders doctor, ...

Phase N/A

Multi-Center Study of Sensory Stimulation to Improve Brain Function

The Overture Study (CA-0005) is a Phase I/II randomized, controlled, single-blind multi-center clinical trial using the GammaSense Stimulation device to study safety, adherence rates and efficacy in subjects with mild to moderate cognitive impairment (MMSE 14-26) who are age 55 and older. Subjects who pass screening will be randomized (ratio ...

Phase N/A

Substance Misuse To Psychosis for Ketamine (SToP-K)

Evidence suggests that repeated or chronic ketamine use, as compared to acute ketamine users, posed a higher clinical risk of developing psychotic disorders, potentially related to the underlying chronic N-methyl-D-aspartate receptor (NMDAR) dysfunction, and a higher risk of suffering from schizophrenia particularly in those genetically susceptible, or genetically predisposed ketamine ...

Phase N/A

Anti-viral Therapy in Alzheimer's Disease

Many viruses are latent for decades before being reactivated in the brain by stress, immune compromise, or other factors. After the initial oral infection, herpes simplex virus-1 (HSV1) becomes latent in the trigeminal ganglion and can later enter the brain via retrograde axonal transport, often targeting the temporal lobes. HSV1 ...


Research Into Antipsychotic Discontinuation and Reduction

Who can participate? Adults who have been diagnosed with schizophrenia, psychosis or a similar condition and are taking antipsychotic medication. What does the study involve? Once a person agrees to take part, they are randomly selected to receive either the 'antipsychotic reduction programme' or 'maintenance treatment'. The 'antipsychotic reduction programme' ...


Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive debilitating and fatal neurodegenerative disease involving the motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord with 5,000 newly diagnosed patients per year in the USA. There is a pressing need for additional therapies, as the only two FDA-approved ...