Search Medical Condition
Please enter condition
Please choose location
Clear Trial Filters
 

Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (5) clinical trials

Safety Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil).

This is a study to evaluate safety, tolerability and PK of DKF-310 IM injection in healthy male volunteers.

Phase

I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD

Participants with Alzheimer's Disease (AD) (up to 8) will receive up to two PET/CT scans with 11C‐BU99008, a tracer alone and then a tracer scan following the administration of idazoxan. In addition, each participant will receive a structural MRI to enable anatomical registration of the PET data. These will enable ...

Phase N/A

The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia

The primary objectives of this application are to determine if the selective ERβ agonist LY500307, when added to antipsychotic medications, improves negative and/or cognitive symptoms in patients with schizophrenia. The specific hypotheses to be tested are to determine if LY500307 is safe and well tolerated in this population and whether ...

Phase

A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males

A Phase 1, Single-centre, Double-blind, Placebo controlled Crossover Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Male Participants

Phase

Safety Tolerability and Pharmacokinetics of AUT00206 in Patients With Schizophrenia and Also Explores the Effects of AUT00206 on Relevant Central Biomarkers.

This study will investigate the safety, tolerability, PK and PD profile of AUT00206 after repeated doses in patients with stable but symptomatic schizophrenia, taking one or two established anti-psychotic drugs. The subjects will undergo brain imaging, tests of cognition and tests of auditory function and electrophysiological measures in addition to ...

Phase