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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (12) clinical trials

A research study is evaluating an investigational medication for mild Alzheimer’s Disease dementia. This research study may be an option for your loved one if: They are 55-85 years of age They have a diagnosis of mild Alzheimer’s Disease dementia All their medication is stable for at least 30 days ...

Phase N/A

Are you (or someone you know) agitated and/or anxious about memory changes due to dementia or Alzheimer’s disease? If so, please call Meridien Research to schedule a screening for a medical research st

Phase N/A

Safety Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil).

This is a study to evaluate safety, tolerability and PK of DKF-310 IM injection in healthy male volunteers.

Phase

I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD

Participants with Alzheimer's Disease (AD) (up to 8) will receive up to two PET/CT scans with 11CBU99008, a tracer alone and then a tracer scan following the administration of idazoxan. In addition, each participant will receive a structural MRI to enable anatomical registration of the PET data. These will enable ...

Phase N/A

The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia

The primary objectives of this application are to determine if the selective ER agonist LY500307, when added to antipsychotic medications, improves negative and/or cognitive symptoms in patients with schizophrenia. The specific hypotheses to be tested are to determine if LY500307 is safe and well tolerated in this population and whether ...

Phase

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study

Cognitive skills are the crucial abilities required to manage money, maintain employment, and live independently. Long-term cognitive impairment (LTCI) is a disabling loss of these skills that can persist for months to years. LTCI frequently occurs after primary brain injury (e.g., traumatic brain injury, hypoxia), but older LTCI research has ...

Phase N/A

A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males

A Phase 1, Single-centre, Double-blind, Placebo controlled Crossover Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Male Participants

Phase

Safety Tolerability and Pharmacokinetics of AUT00206 in Patients With Schizophrenia and Also Explores the Effects of AUT00206 on Relevant Central Biomarkers.

This study will investigate the safety, tolerability, PK and PD profile of AUT00206 after repeated doses in patients with stable but symptomatic schizophrenia, taking one or two established anti-psychotic drugs. The subjects will undergo brain imaging, tests of cognition and tests of auditory function and electrophysiological measures in addition to ...

Phase

Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases

The aim of the present study is to test the effect of a 15-day treatment with memantine on a mixed battery associating cognitive assessment, imaging and neurophysiological tests in healthy volunteers. This multicenter, randomized, placebo-controlled, cross-over study is double-blind controlled and is conducted in 3 centers located in France (Lille, ...

Phase

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

The aim of the present study is to assess the availability of cannabinoid receptors (CB1R) in the human brain. CB1R are present in everyone's brain, regardless of whether or not someone has used cannabis. The investigators will image brain cannabinoid receptors using Positron Emission Tomography (PET) imaging and the radioligand ...

Phase N/A