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Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (176) clinical trials

The Implication of ctDNA in the Recurrence Surveillance of Stage II and III Colorectal Cancer

This study will evaluate circulating tumor DNA (ctDNA) as a prognostic marker and as a monitor of a short-term disease recurrence in surgical resective stage II and stage III colorectal cancer (CRC). The investigators will recruit newly diagnosed CRC patients, systematically collect their blood samples at the following time point: ...

Phase N/A

Longitudinal Performance of Epi proColon

Epi proColon is blood based screening test for colorectal cancer that is FDA - PMA approved. It is indicated for average risk patients who are unwilling or unable to be screened with other recommended screening tests, including colonoscopy or fecal occult blood tests. The PERT study is designed to assess ...

Phase N/A

Diffusion-Weighted MRI for Liver Metastasis

The advancements of systemic and local therapies for complex CRLM have led to the increased incidence of DLMs. It is hypothesized that DW-MRI imaging could distinguish between a metastasis not completely sterilized by conversion therapy and a sterilized scar (non-viable tumor). If this can be demonstrated, the use of DW-MRI ...

Phase N/A

Genetic Risk: Whether When and How to Tell Adolescents

The investigators currently lack an adequate understanding of how parents and children feel about genetic risk/status, how it is communicated, and how it influences wellbeing and family relationships. This understanding is vital in order for genetic counselors and other health care professionals to provide the best guidance possible to families. ...

Phase N/A

Studying Lymph Nodes in Patients With Stage II Colon Cancer

OBJECTIVES Determine whether the immunohistochemical and molecular presence of micrometastases in 12 lymph nodes removed during en-bloc resection in patients with stage II colon cancer correlates with 3-year disease-free survival. Evaluate the prognostic significance of molecular markers detected in the primary tumor and develop a microarray-based gene signature for stage ...

Phase N/A

Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes

This is an observational, case-control study evaluating the quantitative level of Septin9 in plasma pre- and post-colectomy in hereditary colorectal cancer (CRC) syndrome patients (Familial Adenomatous Polyposis (FAP), Lynch syndrome (also known as HNPCC), and Multiple Adenomatous Polyposis (MAP, also known as MYK/MYH) cases) and genetically related FAP-family members as ...

Phase N/A

Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal Cancer

All the preoperative biopsies of patients suffering colorectal cancer (CRC) will be immunohistochemically stained with a pancytokeratin marker to detect Tumor buds. then, the intratumoral buds (ITB) in the densest Region of Tumor buds, namely the "hot spot" will be counted. Subsequently, the probability of N stage (lymphnodes), M stage ...

Phase N/A

Colorectal Cancer Umbrella Protocol - Assessment of Targeted Therapies Against Colorectal Cancer (ATTACC Program) Screening Protocol

The effectiveness of drugs used to treat colorectal cancer may be different from person to person. Researchers want to learn if certain biomarkers can be used to help predict which cancer drugs may work better than other drugs in different people with colorectal cancer. Study Participation: If you agree to ...

Phase N/A

PERCIST Criteria for Response Evaluation With Solid Tumors

Newly diagnosed and pre-therapeutic patients with solid tumors, including but not limited to: lung cancer, lymphoma, gastric cancer, breast cancer, colorectal cancer, ovarian cancer, cervical cancer etc. Study sample: based on ongoing retrospective results, the optimal study sample is expected to be >150 cases per each cancer type. Treatment regimen: ...

Phase N/A

Donation of Post Mortem Tumor Tissues

Despite the recent technological advancement in genomic and proteomic, the molecular understanding of clonal evolution in solid tumor patients is hampered by intra tumor heterogeneity (ITH), while remaining essential to the effective treatment of patients. Recent evidence suggests that branched evolutionary tumor growth may contribute to ITH both within a ...

Phase N/A