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Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (233) clinical trials

The Cancer of the Pancreas Screening-5 CAPS5)Study

The Sub Investigator at each site will be responsible for internal monitoring at their site. The site sub Investigator and study team will report any serious adverse events to Principal Investigator and annually report adverse events.

Phase N/A

Cabozantinib and Panitumumab to Treat KRAS Wild-Type Metastatic Colorectal Cancer

There will be three parts to this phase I study: 1) the Combination Dose Finding cohort; 2) the Combination Expansion cohort; and 3) the Monotherapy MET Amplified cohort. In the Combination Dose Finding cohort and the Combination Expansion cohort, we will combine cabozantinib and panitumumab in patients with KRAS wild-type ...

Phase

Dacomitinib Plus PD-0325901 in Advanced KRAS Mutant Malignancies

This is a phase I/II multi-center open-label proof of concept study, consisting of two parts. Part A of this study is designed to identify the recommended phase 2 dose (RP2D) of the combination regimen of dacomitinib plus PD-0325901 in patients with advanced KRAS mutant (KRASm) colorectal cancer (CRC), non-small cell ...

Phase

An Investigational Immuno-therapy Study of Nivolumab and Nivolumab in Combination With Other Anti-cancer Drugs in Colon Cancer That Has Come Back or Has Spread

Allocation: The Microsatellite Instability High (MSI-High) and C4 and C6 Cohort Parts of the trial are Non-randomized, The Non-MSI high Dose Escalation Phase part of the trial contained a randomized portion

Phase

OctavaColon Cancer Blood Tests OctavaGold and OctavaSilver - Blood Tests for the Help in Diagnosis of Colon Cancer Clinical Study Protocol

The clinical objective of this study is to develop two antibody-based blood tests for additional information during colon cancer diagnosis - 1. Highly specific (OctavaGold) - provides additional information to doctors during evaluation of normal population. 2. Highly sensitive (OctavaSilver) - provides additional information to doctors during evaluation of high ...

Phase N/A

A Phase 2 Randomized Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer

Purpose This two-stage study is designed to compare the safety and activity between RRx-001 against regorafenib followed by irinotecan-based therapies in a parallel comparative study. Patients who are suffering from advanced or metastatic (meaning the disease has spread) colorectal cancer are invited to participate in this study. There will be ...

Phase

Ph 1 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced Gastrointestinal Malignancies

Assessment of safety and tolerability of ADI-PEG 20 in combination with folinic acid (leucovorin), fluorouracil and oxaliplatin (FOLFOX) in advanced GI malignancies.

Phase

Stivarga Regulatory Post-Marketing Surveillance Study in Korea

To investigate and collect post-marketing data on the safety of Stivarga in real world practice in its registered indication(s) as required by Health Authority.

Phase N/A

Validation of MMS Test for Cancer Monitoring

The purpose of this study is the validation of MMS test to detect active tumor growth in different cancer types before and after therapy, as well as in the course of therapy and for subsequent relapse control compared to standard methods (clinical examination, imaging, tumor markers). It should be consider ...

Phase N/A

A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer

The primary purpose of Parts A, B, C, D and E of this study is to determine a recommended dose level and schedule of prexasertib (an inhibitor of checkpoint kinase 1 and 2 [CHK1/CHK2] in combination with: - cisplatin (Part A) - cetuximab (Part B) - pemetrexed (Part C) - ...

Phase