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Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (35) clinical trials

Patients are needed to participate in a clinical research study for the treatment of Colorectal Cancer, head and neck cancer, bladder cancer, Carcinoma, Squamous Cell of Head and Neck, Renal Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma, Non-Small Cell Lung Cancer, Breast Cancer, Gastric Adenocarcinoma

This is a phase 1, open-label, multicenter, dose escalation study that will examine the safety profile of SGN-2FF given orally to patients with advanced solid tumors. The primary goal of the study is to identify the maximum tolerated dose (MTD), or optimal biological dose (OBD) that does not exceed the ...


A clinical trial sponsored by Forty Seven, Inc. for a research study for the treatment of Solid Tumors, Colorectal Cancer

This trial will evaluate Hu5F9-G4 in combination with cetuximab. Hu5F9-G4 is a monoclonal antibody which is designed to block a protein called CD47, which is widely expressed on human cancer cells. Blocking CD47 with Hu5F9-G4 may enable the body's immune system to find and destroy the cancer cells. Cetuximab is ...


A clinical trial to evaluate treatments using Durvalumab for patients with Colorectal Cancer, Platinum-resistant Ovarian Cancer

This is a two-part Phase 1/2 dose escalation and dose expansion study of the GMCSFencoding adenovirus, ONCOS-102, in combination with anti-programmed death ligand-1 (PDL1) antibody, durvalumab, in adult subjects with peritoneal disease who have failed prior standard chemotherapy and have histologically confirmed platinum-resistant or refractory epithelial ovarian cancer or colorectal ...


A clinical research study of MK-8353 for the treatment of Colorectal Cancer, Cancer

This study will evaluate the safety, tolerability and preliminary efficacy of MK-8353 when administered in combination with pembrolizumab (MK-3475). There are two parts in this study: Part 1 will be dose escalation and confirmation, and Part 2 will be a cohort expansion. In Part 1, the recommended phase II dose ...


A clinical trial to evaluate treatments using Regorafenib (Stivarga,BAY73-4506) for patients with Colorectal Cancer

To investigate and collect post-marketing data on the safety of Stivarga in real world practice in its registered indication(s) as required by Health Authority.

Phase N/A

A clinical trial seeking patients for a research study of Vemurafenib, Cetuximab, Pertuzumab, Bevacizumab, FOLFOX induction regimen, Trastuzumab, Cobimetinib, Atezolizumab, Fluoropyrimidine (5-FU/LV or capecitabine), 5-FU/LV

This randomized, multi-center, active-controlled, open-label, parallel-group study will investigate the efficacy and safety of biomarker-driven maintenance treatment for first-line mCRC. Participants with mCRC are eligible for entry and cannot have received any prior chemotherapy in the metastatic setting. The entire study duration is anticipated to be approximately 7.5 years.


A Phase 2 clinical study for patients with Colorectal Cancer

Colorectal cancer is a common clinical gastrointestinal cancer. In addition to the early diagnosis of some patients, approximately 50% of patients have had distant metastases at the time of diagnosis. For patients with advanced colorectal cancer, systemic chemotherapy is the main treatment. We consider to add apatinib,a tyrosine kinase inhibitor ...


Patients are needed to participate in a clinical research study of Fluorouracil, Atezolizumab, Leucovorin Calcium, Oxaliplatin

PRIMARY OBJECTIVES: I. To determine whether atezolizumab combined with oxaliplatin, leucovorin calcium, and fluorouracil (FOLFOX) and its continuation as monotherapy can significantly improve disease-free survival (DFS) compared to FOLFOX alone in patients with stage III colon cancers and deficient DNA mismatch repair (dMMR). SECONDARY OBJECTIVES: I. To determine whether atezolizumab ...


A clinical research study for the treatment of Colorectal Cancer

Objectives To start a prospective observational cohort study of CRC patients from their primary diagnosis until death. After obtaining Informed Consent, to prospectively collect data on medical history, serious comorbidities, baseline clinical parameters, imaging results, pathology results, tumor characteristics, treatment, treatment outcomes, hospital stays, interventions and grade 3/4 adverse events. ...

Phase N/A

A Phase 4 clinical study for patients with Malignant neoplasm of colon, Unresectable Metastasis Originating in Colonic Cancer

Intervention: Arm B (control): chemotherapy alone, regimen according to each center. Arm A (experimental): surgery (complete tumoral resection; R0) followed by chemotherapy, regimen according to each center. Statistical Analysis: A power analysis showed that to assure a significance level of 0,05 and a beta error 0.20. 168 patients are necessary ...