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Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (39) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT01150045?term=CALGB+80702&rank=1

Phase

Wound infections can occur in about 12-25% of patients undergoing colorectal surgery despite routine efforts to prevent them. This study is being done to assess the safety and ability of an experimental drug called E-101 Solution (study drug), in addition to routine efforts, to prevent incisional wound infection for 30 ...

Phase

This is a sedation during colonoscopy study. The primary objective of this study is to assess the safety of multiple doses (initial dose and additional top-up doses) of remimazolam compared to placebo and midazolam, following administration of a standard dose of fentanyl. Procedural sedation in adult patients undergoing colonoscopy for ...

Phase

A Phase III Randomized Placebo-Controlled Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Stage III Colon Cancer For Study Locations, Click Here

Phase

The Northern-European Initiative on Colorectal Cancer

Colorectal cancer (CRC) is a major burden in western countries. The disease develops from precursor lesions during a long time-interval. Colonoscopy can detect and remove CRC precursor lesions and may thus be effective for CRC prevention. Many national and international health organisations demand evidence from randomised trials to reduce incidence ...

Phase

-adrenergic Blocker and a COX2 Inhibitor for Prevention of Colorectal Cancer Recurrence

Colon and rectal cancer is the second most prevalent malignant disease in the western world, causing significant morbidity, mortality, and healthcare sources use. Treating colon and rectal cancer with curative intent generally includes resection of the primary tumor. Despite its crucial role, surgery by itself induce physiological changes resulting in ...

Phase

Increasing Colorectal Cancer Screening in African Americans

OBJECTIVES: - To assess the intervention impact on colorectal cancer (CRC) screening utilization over a 6-month observation period in African-American participants. - To assess the intervention impact on CRC screening preference, classified into three levels (i.e., "decided not to screen or never heard of," "undecided," or "decided to screen"), based ...

Phase

Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

OBJECTIVES: - Compare local and distant recurrences in patients with mid-rectal cancer treated with wide mesorectal surgical excision with straight colorectal anastomosis versus total mesorectal surgical excision with colonic J pouch coloanal anastomosis. - Compare the functional, physiological, and anatomical outcomes in these patients treated with these two surgical procedures. ...

Phase

Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil

OBJECTIVES: Primary - Compare the efficacy and toxicity of single-agent irinotecan hydrochloride (Ir) vs Ir with cyclosporine (IrC) in patients with fluorouracil-resistant advanced colorectal cancer. - Compare the efficacy of single-agent Ir vs Ir with panitumumab (IrP) in these patients. Secondary - Correlate the toxicity of Ir and/or IrC with ...

Phase

Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer

OBJECTIVES: Primary - Compare progression-free survival of patients with resectable colorectal liver metastases treated with neoadjuvant and adjuvant combination chemotherapy with vs without cetuximab. Secondary - Compare the overall survival of patients treated with these regimens. - Compare the quality of life of patients treated with these regimens. - Compare ...

Phase