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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (3472) clinical trials

Exact Sciences Corporation, the sponsor of this study, is collecting blood samples to better understand the biomarkers of patients with abnormal CT scans or lung cancer nodules. Biomarkers are biologic features found in the blood and may be related to lung disease risk and detection. The sponsor will also collect ...

Phase N/A

A research study is evaluating an investigational medication that may decrease the risk of cardiovascular events or worsening of heart failure in patients with preserved/normal ejection fraction.  

Phase N/A

A randomized, parallel, placebo controlled trial to evaluate the effect of 100mg/day losartan on the progression of emphysema as measured by quantitative HRCT compared to placebo  

Phase

This trial will be a large-scale, pragmatic, cluster-randomized clinical trial to evaluate the effect of a customized, multifaceted, health system-level quality-improvement (QI) program compared with usual care on heart failure (HF) outcomes and HF quality-of-care metrics. Outcomes will be assessed in the year following discharge for participants hospitalized with acute ...

Phase N/A

The purpose of this study is to evaluate the efficacy and safety of intermittent levosimendan compared with placebo in hemodynamic improvement with exercise in PH-HFpEF subjects  

Phase

Transpulmonary Pressures in Mechanical Ventilated Patients With Morbid Obesity

We are studying adult patients with morbid obesity with respiratory failure requiring mechanical ventilation. We are measuring transesophageal presssures to estimate ideal PEEP and evaluate hemodynamic parameters.

Phase N/A

Study Assessing the Safety Tolerability Pharmacokinetics Food Effect and Drug-Drug Interactions of PTI-801 in Healthy Volunteers and Safety Tolerability and Pharmacokinetics of PTI-801 in Subjects With Cystic Fibrosis

PART 1 The SAD treatment group is comprised of three cohorts where HV will be randomized to either PTI-801 or placebo. Following the conclusion of at least three SAD cohorts, a set of HV will participate in an assigned MAD treatment group. The MAD treatment group is comprised of three ...

Phase

Inflammation and Distribution of Pulmonary Ventilation Before and After Tracheal Intubation in ARDS Patients

We will conduct a prospective clinical protocol in patients admitted to the ICU of the Hospital Clnico UC-Christus, Santiago de Chile, with diagnosis of acute hypoxemic respiratory failure, but who are still ventilating spontaneously. Clinical data: After hospital admission, patients who meet inclusion/exclusion criteria will be asked to consent to ...

Phase N/A

Nashville Early Diagnosis Lung Cancer Project

It is proposed to test the hypotheses in a screening study of high risk individuals (characterized by an established prediction rule). The expected prevalence of lung cancer in this high risk group is estimated to be 2% per year. All individuals benefit from clinic visit, low-dose Chest CT, spirometry and ...

Phase N/A

Integrative-omics of the Disordered COPD Small Airway Epithelium

Hypothesis: We hypothesize that the disordered differentiation of the SAE that characterizes COPD results from the complex interaction of cigarette smoke components with a hierarchy of genetic, epigenetic, gene expression and metabolomics network interactions as the BC differentiate into a mucociliary epithelium. Specific aim 1. Using an integrated network systems ...

Phase N/A