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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (321) clinical trials

Novel Biomarkers in Chronic Airway Diseases

The purpose of this study is: - To define The differences of bio-chemical phenotypes in chronic airway inflammatory diseases. - To identify novel biomarkers in chronic airway inflammatory diseases as a screening, diagnostic, or monitoring marker.

Phase N/A

Systemic Inflammation in Chronic Obstructive Pulmonary Disease (COPD)

COPD is ranked number 3 by the WHO list of important diseases worldwide and is the only disease with increasing mortality. The pathogenesis of cigarette smoke-induced COPD is obscure, therefore more insight is needed to design effective anti-inflammatory agents. Recently it has become clear that cigarette smoke-induced inflammation is not ...

Phase N/A

Serum Plasma DNA and Tissue Bank in Chronic Obstructive Pulmonary Disease and Lung Cancer

All patients with a smoking history of at least 15 pack years, an minimal age of 50 years and an recent available CT scan are enrolled. All subjects with a diagnosis of lung cancer are also collected (irrespective of age and smoking behavior). In addition the investigators collect: - specific ...

Phase N/A

Gene-expression Profiles in CNS-metastatic Non-small Cell Lung Cancer

Brain metastases occur in 30-50% of lung adenocarcinoma (LAC) patients and confer a worse prognosis and quality of life. A better selection of in-risk patients through a more accurate biomarker could improve the benefit of prophylactic therapies. The aim of this prospective study was to determine a gene-expression profile of ...

Phase N/A

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

In the United States, a variety of farming operations can generate significant amounts of dust. Chronic organic dust exposure to workers in this industry can result in several respiratory health conditions including chronic bronchitis, chronic obstructive pulmonary disease (COPD), and exacerbations of asthma. Organic dust is a complex mixture containing ...

Phase N/A

Microbiology and Clinical Outcome of Pneumonia

BACKGROUND Pneumonia occurring outside of the hospital setting is regarded as community acquired pneumonia. However, pneumonia occurring in non-hospital long-term care facilities constituted a distinct type of pneumonia from CAP. Kollef et al has justified health care associated pneumonia (HCAP) as a new category of pneumonia . The HCAP patients ...

Phase N/A

Evolution of Management Strategies of Heart Failure Patients With Implantable Defibrillators

Heart failure patients with implantable defibrillators (ICD) perform frequent clinic visits for routine device monitoring. Moreover, in case of clinical events, such as ICD shocks or alert notifications for changes in cardiac status or safety issues, they often visit the emergency department or the clinic for an unscheduled visit. These ...

Phase N/A

Pilot Study: Hypovitaminosis D Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure

People with heart failure may have low magnesium and low vitamin D levels. They may also have abnormally high levels of parathyroid hormones. Magnesium and vitamin D are important chemicals that are not routinely measured in blood tests. We are studying how many people with heart failure have low levels ...

Phase N/A

Synchronized Intermittent Mechanical Ventilation Versus Open Lung Ventilation With Spontaneous Respiration

SOLV Hypothesis: A prospective, randomized trial directly comparing open lung ventilation (OLV) with spontaneous breathing (SB) utilizing BiVent on the Maquet Servo-I versus synchronized intermittent mechanical ventilation (SIMV) will be conducted in the trauma-surgical intensive care unit at the University Hospital (TSICU). Both OLV-SB and SIMV protocols have been designed ...

Phase N/A

Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer

OBJECTIVES: - Develop statistical and computational methods for modeling the relationships between multiple variable protein and RNA expression data and clinical endpoints using both supervised and unsupervised classification and pattern recognition approaches. - Determine protein and RNA expression fingerprints on completely resected non-small cell lung cancer without prior chemotherapy. - ...

Phase N/A