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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (186) clinical trials

This study includes up to 12 visits to our office over a maximum time of 36 months. It may end sooner based upon results. Breathing tests, physical exams, vital signs, ECG's, blood and urine tests will all be performed throughout the study. Visits to our office are infrequent over the ...


Patients With Chronic Obstructive Pulmonary Disease at Altitude - Effect of Nocturnal Oxygen on Breathing and Sleep

Patients with moderate to severe chronic obstructive pulmonary disease living below 800 m will be invited to participate in a randomized, cross-over field trial evaluating the hypothesis that nocturnal breathing and sleep during nights spent at moderate altitude are improved by oxygen therapy via a nasal cannula compared to room ...


Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing and Sleep

Patients with pulmonary hypertension or with interstitial lung disease living below 800 m will be invited to participate in a randomized, cross-over field trial evaluating the hypotheses that: a), breathing and sleep during a 2 day sojourn at moderate altitude are impaired in comparison to low altitude; b), breathing and ...


Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

The primary objective of this study is to test whether a standardized Left Ventricular Reconstruction (LVR) performed with the Blue Egg device improves cardiopulmonary exercise capacity in subjects with stable New York Heart Association (NYHA) Class III or IV heart failure due to ischemic cardiomyopathy with an akinetic or dyskinetic ...


Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair

Elective surgical repair of a Thoraco (Abdominal) Aneurysm Aorta (T(A)AA) is associated with high mortality and morbidity. Important complications are renal failure, paraplegia and respiratory failure. A retrospective study we performed also revealed high post operative infection rates and high incidence of respiratory failure. Improving immune status may reduce the ...


Early CPAP in Respiratory Distress Syndrome

The application of CPAP has been described as an alternative respiratory support for premature newborns with respiratory distress.Many studies support that the early use of CPAP results in a better respiratory evolution and less need for mechanical ventilation. Hypothesis: - The hypothesis is that EBCPAP will decrease the need for ...


PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing

The course of patients with chronic heart failure is marked by periodic episodes of clinical decompensation that not only impair the quality of life and may be fatal but also consume substantial health care resources, primarily due to the costs of hospitalization. Heart failure management programs have been developed to ...


Bronchoprotection of Salbutamol in Asthma and Chronic Obstructive Pulmonary Disease

In asthma, the administration (inhalation) of a selective 2 receptor agonist (e.g. salbutamol), prior to methacholine challenge has been shown to shift the dose response curve to the right and "bronchoprotect" the airway against airway smooth muscle contraction. The extent of 2 receptor agonist bronchoprotection in COPD is unknown. Airway ...


Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children

Introduction Extensive surveys have shown that 6-20 % of children have acute expiratory wheezing (1, 2). The lifetime prevalence of wheezing among 12–14-year-old children in the Western countries is 8-19 % (3, 4). The clinical illness is called bronchiolitis when occuring for the first time in infants younger than 12 ...


Oxygen Versus PAP for Sleep Apnea in Heart Failure

Chronic heart failure (HF) is a highly prevalent disease, with a lifetime risk of approximately 20%. Sleep apnea is a common co-morbid condition, occurring in approximately half of patients with chronic HF, and often has predominantly central or mixed obstructive and central characteristics. Although it is associated with increased mortality ...