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Heart Failure Clinical Trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (784) clinical trials

A global registry to study the demographics, socioeconomic and clinical factors, etiologies, pathophysiology, management, barriers to care, and outcomes of heart failure patients.

Phase N/A

A research study is evaluating the effects of an investigational study medication for heart failure in patients with iron deficiency.

Phase N/A

To evaluate the safety and efficacy of a once daily oral medication compared to a placebo, in patients with chronic Heart Failure with preserved Ejection Fraction.


To evaluate the effect of treatment with omecamtiv mecarbil (OM) compared with placebo on the time to cardiovascular (CV) death or first HF (Heart Failure) event, whichever occurs first, in subjects with chronic HF with reduced ejection fraction (HFrEF) receiving standard of care (SoC) therapy.

Phase N/A

To evaluate the efficacy of the oral soluble guanylate cyclase (sGC) stimulator MK-1242 (vericiguat) in comparison to placebo on a background of standard of care in increasing the time to first occurrence of the composite of CV death or HF hospitalization in subjects with HFrEF.

Phase N/A

HeartMate 3 ELEVATE

The purpose of this post-market registry is to collect data and evaluate the real-world experience of the HeartMate 3 Left Ventricular Assist System (HM3 LVAS) in a post-approval setting.

Phase N/A

CORolla TAA for Heart Failure With Preserved Ejection Fraction (HFpEF) and Diastolic Dysfunction (DD)

The study objective is to demonstrate safety and feasibility of the CORolla TAA during 12 months of follow up, and to evaluate the performance of the therapy in relieving symptoms and restore diastolic function in patients with heart failure and preserved ejection fraction.

Phase N/A

Prevalence of Chronic Kidney Disease and Its Association With Clinical Outcome in Patients With Coronary Heart Disease

The primary aim of the study is to evaluate the prevalence of chronic kidney disease(CKD) in patients with stable coronary heart disease. The secondary aims include: 1. To evaluate the awareness of CKD in patients with stable coronary heart disease. 2. To find out risk factors that is associated with ...

Phase N/A

Increased Adsorption Membranes During Cardiopulmonary Bypass

After informed consent, on those patients randomized to CPB-OXIRIS, PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will be irrigated with saline during preparation and irrigation of CPB circuit. PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will then be connected to CPB circuit. Blood flow between 200-250 ml/min will ...

Phase N/A

MultiPoint Pacing Mapping Study

The purpose of this study is to characterize left ventricular acute hemodynamic and electrical responses during cardiac resynchronization therapy (CRT) with different Multipoint Pacing (MPP) settings, and assess the relationship between electrical activation patterns and hemodynamic measurements during these pacing settings.

Phase N/A