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Heart Failure Clinical Trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (505) clinical trials

Sensible Medical Innovations Lung fLuid Status Monitor Allows rEducing Readmission Rate of Heart Failure Patients

The study is designed as a prospective, randomized, controlled, multi-center trial. Patients will be enrolled during an index hospitalization for Acutely decompensated Heart Failure (ADHF) and will be followed for a minimum of 3 months or a maximum of 9 months (until the last patient has completed the 3- month ...

Phase N/A

Assessment of Cardiac Resynchronization Therapy in Patients With Wide QRS and Non-specific Intraventricular Conduction Delay: a Randomized Trial

This is a pilot, prospective, controlled, two-parallel arm, randomized, double-blind design and multicentric clinical trial comparing a CRT-D or CRT-P ON group vs. CRT-D or CRT-P OFF group in HF with reduced ejection fraction patients with NICD. Patients will be included in twelve French centers (Clermont-Ferrand University Hospital, Cte Basque ...

Phase

Syncardia 50cc TAH-t as a Bridge to Transplant

Heart failure is the reduced ability of the native heart to pump blood and maintain normal bodily function. Heart transplantation is the standard of care treatment for end-stage heart failure but the supply of donor hearts is insufficient to meet the need and many patients are not eligible for transplantation ...

Phase N/A

Determine Return on Investment in Heart Failure Remote Monitoring Program

The objective of this remote monitoring study is to evaluate return on investment and end-user clinical outcomes associated with the use of self-monitoring peripherals and tablet/smartphone-based Welch Allyn HealthInterlink technology without intervention (Control), HealthInterlink remote monitoring with text and email alerts sent to study subject and optional family/other caregiver (Intervention ...

Phase N/A

Quartet Lead and Resynchronization Therapy Options III (QUARTO III)

The primary endpoint of the study is to measure prospectively at 6 months the percentage of responder* patients implanted with a Quartet LV quadripolar lead and with the MultiPoint Pacing feature activated compared with No Pacing at baseline. *A positive CRT response is defined as an improvement of more than ...

Phase N/A

Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support

This time point was chosen because the bleeding events are maximal within the first 3 months after implantation. Adult patients > 18 years who need a CF-LVAD due to advanced heart failure. Functional To determine the potential indication of Wilfactin in the field of CF-LVAD and avoid widespread use and ...

Phase

CORolla TAA for Heart Failure With Preserved Ejection Fraction (HFpEF) and Diastolic Dysfunction (DD)

The study objective is to demonstrate safety and feasibility of the CORolla TAA during 12 months of follow up, and to evaluate the performance of the therapy in relieving symptoms and restore diastolic function in patients with heart failure and preserved ejection fraction.

Phase N/A

Increased Adsorption Membranes During Cardiopulmonary Bypass

After informed consent, on those patients randomized to CPB-OXIRIS, PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will be irrigated with saline during preparation and irrigation of CPB circuit. PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will then be connected to CPB circuit. Blood flow between 200-250 ml/min will ...

Phase N/A

MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint Pacing

This study is designed as a prospective, randomized, multi-center trial. Data will be collected at enrollment, baseline, implant procedure, patient classification, 6 months and 12 months of follow-up. During the 6-month visit, the patient's response to CRT will be evaluated according to LVESV reduction. Patients with an LVESV reduction of ...

Phase N/A

Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure.

The purpose of this study is to evaluate the efficacy and safety of a single transendocardial delivery in the cardiac catheterization laboratory of human bone marrow-derived allogeneic MPCs (rexlemestrocel-L) for improvement in clinical outcomes (HF-MACE), preventing further adverse cardiac remodeling (LVESV and LVEDV), and increasing exercise capacity (6MWT) in patients ...

Phase