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Heart Failure Clinical Trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (35) clinical trials

The purpose of this study is to investigate if rivaroxaban in combination with standard care (the other medications you are currently taking for your heart failure (HF) and coronary artery disease (CAD)) can reduce the risk of a heart attack, stroke or death in patients with Chronic Heart Failure and ...

Phase

The purpose of this study is to see if starting sacubitril/valsartan (Entresto) while in the hospital, as compared to Enalapril, will have an effect on the blood test called NT-proBNP, that reflects elevated pressures or stress on the heart, in patients that have been hospitalized for a type of heart ...

Phase

This is an event-driven Phase IIIb, multicentre, randomised, clinical study to demonstrate the efficacy of AdreView™ imaging for appropriately guiding the decision of implantable cardioverter defibrillator (ICD) implantation, in New York Health Association (NYHA) class II and III heart failure patients with 30%=left ventricular ejection fraction (LVEF)=35%%, and in particular, ...

Phase

The objective of this event-driven trial is to demonstrate superiority of empagliflozin 10 mg versus placebo in patients with symptomatic, chronic HF and preserved ejection fraction (LVEF > 40%) under stable treatment of HF symptoms. The trial will be performed in patients with chronic heart failure with an ejection fraction ...

Phase

The objective of this event-driven trial is to demonstrate superiority of empagliflozin 10 mg versus placebo on top of guideline-directed medical therapy in patients with symptomatic, chronic HF and reduced ejection fraction (LVEF ≤ 40%). Patients with chronic HF diagnosed for at least 3 months before Visit 1.

Phase

The primary objective of this study is to assess the effect of oral treprostinil compared with placebo on change in exercise capacity as measured by change in 6MWD from Baseline to Week 24 in subjects with PH associated with HFpEF. There are no approved treatments for PH in subjects with ...

Phase

Intravenous Iron in Patients With Severe Chronic Heart Failure and Chronic Kidney Disease

Intravenous iron administration in CHF patients with absolute or functional iron deficiency could correct their anemia, thus improving cardiac function judged by ejection fraction and NYHA functional class. If true, enhancement of cardiac output will increase oxygen delivery to tissues, including renal cortex. This might improve the renal functions and ...

Phase

Trial of Education and Compliance in Heart Dysfunction (TEACH)

INTRODUCTION: Heart Failure (HF) is one of the leading causes of hospitalization in Canada. While great advances have been made in the treatment of this disease, factors limiting the effectiveness of treatment include: poor compliance to dietary guidelines and medications, patients' lack of understanding about the impact of their disease, ...

Phase

Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support

This time point was chosen because the bleeding events are maximal within the first 3 months after implantation. - Adult patients > 18 years who need a CF-LVAD due to advanced heart failure. - Functional To determine the potential indication of Wilfactin® in the field of CF-LVAD and avoid widespread ...

Phase