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Brain Cancer Clinical Trials

A listing of Brain Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found (495) clinical trials

You are being asked to take part in this study because you have a type of brain tumor called a glioblastoma multiforme (GBM) and you have completed the first part of your treatment with radiation combined with the chemotherapy drug temozolomide (TMZ). The standard treatment after completing radiation is to ...

Phase N/A

You are being asked to take part in this study because you are experiencing fatigue that is related to your cancer. Cancer related fatigue is a very common symptom in people with cancer. The purpose of this study is to: See if taking the study agent, armodafinil, at a dose ...

Phase

People with Glioblastoma are asked to participate in a research study being conducted by Northshore University Hospital.

Phase N/A

To demonstrate the antitumor activity of Antineoplaston A10 and AS2-1 in the treatment of children with primary malignant brain tumors by determining the proportion of patients who experience an objective tumor response. To evaluate the adverse effects and tolerance of Antineoplaston A10 and AS2-1 in these patients. Inclusion Criteria Patients ...

Phase

An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

There are a variety of tumors affecting the pituitary gland; The gene(s) involved in the pathogenesis of these tumors are largely not known; their possible association with other developmental defects or inheritance pattern(s) has not been investigated. The present study serves as a (i) screening/training, and, (ii) a research protocol. ...

Phase N/A

Study of Skin Tumors in Tuberous Sclerosis

Patients with tuberous sclerosis develop benign cutaneous tumors that are typically multiple in number and location. These tumors include facial angiofibromas, forehead plaques, shagreen patches, periungual fibromas, and gingival fibromas. The tumors are permanent, slow growing, and often disfiguring. The purpose of this study is to elucidate the molecular basis ...

Phase N/A

Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors

OBJECTIVES: - Determine the maximum tolerated dose of benzoporphyrin monoacid ring A in patients with refractory brain tumors undergoing cavitary photoillumination photodynamic therapy. - Determine the effect of this regimen on neurotoxicity, clinical state, imaging changes, and survival of these patients. OUTLINE: This is a dose-escalation study. Patients are stratified ...

Phase

Study of Individuals and Families at High Risk for Cancer

OBJECTIVES: - Identify individuals at high risk of cancer, especially due to personal or family medical history. - Evaluate and define clinical spectrum of disease in syndromes predisposing to cancer. - Quantify risks of tumors in family members. - Map, clone, and determine function of tumor susceptibility genes. - Identify ...

Phase N/A

Natural History of Patients With Brain and Spinal Cord Tumors

Background: This protocol is designed to evaluate patients with tumors of the central nervous system (CNS) who appear to be probable candidates for future protocol entry or have disease manifestations that are of unique scientific interest, importance, and/or educational value. Objective: To evaluate patients with tumors of the central nervous ...

Phase N/A

Screening Patients With Central Nervous System Tumors for Participation in National Cancer Institute Clinical Trials

OBJECTIVES: - Evaluate patients with central nervous system tumors for eligibility in NCI primary clinical research protocols. OUTLINE: Patients undergo various diagnostic procedures and clinical testing to determine eligibility for participation in NCI CNS tumor primary clinical research protocols. Patients undergo imaging scans; laboratory testing of blood, cerebrospinal fluid, bone ...

Phase N/A