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Brain Cancer Clinical Trials

A listing of Brain Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (218) clinical trials

To demonstrate the antitumor activity of Antineoplaston A10 and AS2-1 in the treatment of children with primary malignant brain tumors by determining the proportion of patients who experience an objective tumor response. To evaluate the adverse effects and tolerance of Antineoplaston A10 and AS2-1 in these patients. Inclusion Criteria Patients ...

Phase

You are being asked to take part in this study because you have a type of brain tumor called a glioblastoma multiforme (GBM) and you have completed the first part of your treatment with radiation combined with the chemotherapy drug temozolomide (TMZ). The standard treatment after completing radiation is to ...

Phase N/A

You are being asked to take part in this study because you are experiencing fatigue that is related to your cancer. Cancer related fatigue is a very common symptom in people with cancer. The purpose of this study is to: See if taking the study agent, armodafinil, at a dose ...

Phase

A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis

Metastatic melanoma is an aggressive tumor associated with very poor prognosis. Brain metastases develop in nearly half of MM pts and in 30 to 40% of these subjects, the brain is the first site of relapse. The limited activity of available agents, along with relative resistance to radiotherapy and poor ...

Phase

Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

This is a randomized double-blinded phase II study of corticosteroids with bevacizumab vs. corticosteroids with placebo for brain radionecrosis following radiosurgery for brain metastases. This is a two-arm clinical trial with parallel group design for longitudinal quality of life endpoint. Patients will be stratified according to age (≤ 65 years ...

Phase

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Primary Objectives - To investigate by magnetic resonance (MR) imaging the spatial and temporal distribution of topotecan in tumor-infiltrated brain administered by convection-enhanced delivery (CED) in patients with recurrent/progressive WHO grade III or IV (high grade) glioma (HGG) who have failed standard therapy comprising surgical biopsy and/or resection and adjuvant ...

Phase N/A

Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas

PRIMARY OBJECTIVES: I. To determine the activity of a smoothened, frizzled class receptor (SMO) and PTCH1 inhibitor in patients with meningiomas harboring SMO mutations as measured by 6-month progression free survival (PFS) and response rate. II. To determine the activity of a FAK inhibitor in patients with meningiomas harboring neurofibromin ...

Phase