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Benign Prostatic Hyperplasia (Enlarged Prostate) Clinical Trials

A listing of Benign Prostatic Hyperplasia (Enlarged Prostate) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (47) clinical trials

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

This clinical trial is designed as a randomized, placebo-controlled, multi-center phase 2 trial to evaluate the efficacy and safety of OPK-88004 in men with benign prostatic hyperplasia. Eligible subjects will be randomized into one of two OPK-88004 treatment groups or a placebo group after a 4-week screening period. Subjects will ...


A Study to Evaluate the Efficacy Safety and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

At Screening (Visit 1), subjects will enter into a 4-week open label tamsulosin hydrochloride 0.4 mg QD run-in period prior to being randomized into the 12-week double-blind treatment period (Visit 2). At conclusion of the 4-week tamsulosin hydrochloride run-in period, subjects will complete a 3-day diary just prior to Baseline ...


Bipolar Transurethral Enucleation (BipolEP) vs Bipolar Transurethral Resection of the Prostate

Overview The aim of this study is to compare two different surgical methods for treating benign prostatic obstruction (BPO). The investigators are going to compare the risks and benefits of bipolar transurethral resection of the prostate (TURP) and bipolar transurethral enucleation of the prostate (BipolEP). Furthermore, the investigators are going ...

Phase N/A

Taiwan ACE Beads for Embolization Therapy in Symptomatic Benign Prostatic Hyperplasia

T-ACE Beads can be used for prostatic arterial embolization safely and efficiently. Furthermore, investigator's microspheres has advantageous characteristics in biodegradability, drug delivery capability, and cost-effectiveness. After the clinical trial, we anticipate introducing a new microsphere for Lower Urinary Tract Symptom/Benign prostatic hyperplasia patients, which is beneficial to the participants in ...

Phase N/A

Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible ...

Phase N/A

Study to Assess the Efficacy of the iTind in Subjects With Symptomatic BPH

Primary Study Objective: The study's primary objective is to assess the efficacy of the MediTate iTind in subjects with symptomatic BPH by reduction of IPSS ) (International Prostate Symptoms Score) score. Secondary Study Objectives: To further evaluate the efficacy of MediTate iTind as determined by increase of maximal urinary peak ...

Phase N/A

Study to Assess the Tolerability Safety and Efficacy of (iTIND)

Subjects with AUR secondary to BPO that comply with Inclusion/Exclusion Criteria. A total of 44 eligible subjects will be randomized into the study to receive treatment with either re-catheterization OR with iTind implantation using a 1:1 randomization scheme stratified by center. Study duration will be 12 months post implantation, with ...

Phase N/A

Prostate Artery Embolization (PAE) for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

This is a investigator-initiated evaluation of the safety and efficacy of treating benign prostatic hyperplasia (BPH) by prostatic artery embolization.


Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy

Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder. Compression of the urethra is common cause of such resistance of full draining, and may over time result in progressive hypertrophy, instability, urgency, nocturia and weakness ...


High Power Thulium Vaporization vs Transurethral Resection of the Prostate for Treatment of BPH

When Lower Urinary Tract Symptoms (LUTS) are refractory to medical therapy and bothersome enough to warrant surgical intervention, transurethral resection of the prostate (TURP) has been the historical reference-standard procedures for prostate size between 30-80 ml for years. Over the past decade, New minimally invasive surgical therapies (MIST), new medications, ...

Phase N/A