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Benign Prostatic Hyperplasia (Enlarged Prostate) Clinical Trials

A listing of Benign Prostatic Hyperplasia (Enlarged Prostate) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (43) clinical trials

Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With Benign Prostatic Hyperplasia and Lower Urinary Track Symptoms (BPH)

This proposed intervention is the first randomized clinical trial comparing the effects of onaBoNT-A prostate injection versus alpha adrenergic antagonist medication for LUTS associated with BPH. Up to this point, clinical studies using onaBoNT-A in the prostate has been limited to patient's refractory to -1 adrenoceptor blocker therapy. The study ...


Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

This clinical trial is designed as a randomized, placebo-controlled, multi-center phase 2 trial to evaluate the efficacy and safety of OPK-88004 in men with benign prostatic hyperplasia. Eligible subjects will be randomized into one of two OPK-88004 treatment groups or a placebo group after a 4-week screening period. Subjects will ...


A Study to Evaluate the Efficacy Safety and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)

At Screening (Visit 1), subjects will enter into a 4-week open label tamsulosin hydrochloride 0.4 mg QD run-in period prior to being randomized into the 12-week double-blind treatment period (Visit 2). At conclusion of the 4-week tamsulosin hydrochloride run-in period, subjects will complete a 3-day diary just prior to Baseline ...


Optilume BPH Prostatic Drug Coated Balloon Dilation Catheter

A prospective, non-randomized, multi-center early feasibility study. The study will enroll up to 65 subjects to be enrolled and treated with the Optilume BPH Prostatic DCB Dilation Catheter System at up to 15 clinical sites. Subjects will be followed up post-treatment at Foley removal, and up to 1 year. The ...


Bipolar Transurethral Enucleation (BipolEP) vs Bipolar Transurethral Resection of the Prostate

Overview The aim of this study is to compare two different surgical methods for treating benign prostatic obstruction (BPO). The investigators are going to compare the risks and benefits of bipolar transurethral resection of the prostate (TURP) and bipolar transurethral enucleation of the prostate (BipolEP). Furthermore, the investigators are going ...

Phase N/A

Taiwan ACE Beads for Embolization Therapy in Symptomatic Benign Prostatic Hyperplasia

T-ACE Beads can be used for prostatic arterial embolization safely and efficiently. Furthermore, investigator's microspheres has advantageous characteristics in biodegradability, drug delivery capability, and cost-effectiveness. After the clinical trial, we anticipate introducing a new microsphere for Lower Urinary Tract Symptom/Benign prostatic hyperplasia patients, which is beneficial to the participants in ...

Phase N/A

Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible ...

Phase N/A

Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Using Bead Block Microspheres

This pilot study will be a single center, open labeled, non-randomized feasibility study to evaluate the initial safety of PAE for the treatment of symptomatic bladder outlet obstruction. 30 adult male subjects will be enrolled in this study. If eligible patients will undergo the prostate artery embolization procedure in the ...

Phase N/A

Study to Assess the Efficacy of the iTind in Subjects With Symptomatic BPH

Primary Study Objective: The study's primary objective is to assess the efficacy of the MediTate iTind in subjects with symptomatic BPH by reduction of IPSS ) (International Prostate Symptoms Score) score. Secondary Study Objectives: To further evaluate the efficacy of MediTate iTind as determined by increase of maximal urinary peak ...

Phase N/A

Study to Assess the Tolerability Safety and Efficacy of (iTIND)

Subjects with AUR secondary to BPO that comply with Inclusion/Exclusion Criteria. A total of 44 eligible subjects will be randomized into the study to receive treatment with either re-catheterization OR with iTind implantation using a 1:1 randomization scheme stratified by center. Study duration will be 12 months post implantation, with ...

Phase N/A