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Blood Cancer Clinical Trials

A listing of Blood Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (1161) clinical trials

Intensification Therapy of Mature B-ALL Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults

All patients are treated according to the same therapy regimen. Therapy duration (number of cycles) and radiotherapy vary according to age group, stage and response. Chemotherapy consists of a pre-phase-treatment (for all patients) and varying A, B and C cycles. Therapy for Patients in the 18-55 Age Group - Patients ...


Study of Radiation Exposure in Chernobyl Clean-up Workers With Leukemia Multiple Myeloma or Myelodysplasia

OBJECTIVES: Primary - To test the hypothesis that there is a dose-related increase in risk of leukemia in the liquidators involved in the cleanup work after the Chernobyl Nuclear Power Plant accident in northern Ukraine in 1986. - To test the hypothesis that the magnitude of any observed risk per ...

Phase N/A

Comparison of Fecal Ribonucleic Acid (RNA) Test With Fecal Occult Blood Test (FOBT) for Detecting Colorectal Cancer and Adenoma

Colorectal cancer (CRC) is the second common cause of death in the Western world, and is very increasing in Japan. Fecal occult blood test (FOBT) is used routinely for CRC screening, which has been shown to reduce the incidence, morbidity, and mortality of CRC. However, there is a need to ...

Phase N/A

Rituximab Cyclophosphamide Vincristine Sulfate and Prednisone With or Without Liposome-Encapsulated Doxorubicin Citrate in Treating Older Patients With Stage II Stage III or Stage IV Diffuse Large B-Cell Non-Hodgkin Lymphoma

OBJECTIVES: Primary - To assess the therapeutic efficacy of rituximab, cyclophosphamide, vincristine sulfate, and prednisone with vs without liposome-encapsulated doxorubicin citrate, in terms of complete remission rate at 6 months, in vulnerable or frail elderly patients with stage II, III, or IV diffuse large B-cell non-Hodgkin lymphoma. - To assess ...


Cyclophosphamide Fludarabine Total-Body Irradiation and Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer or Other Disease

OBJECTIVES: Primary - Determine, preliminarily, the efficacy of double-unit umbilical cord blood (UCB) transplantation (UCBT) in patients with hematologic malignancy. Secondary - Determine the incidence and rate of donor-derived neutrophil and platelet recovery in these patients. - Determine the contribution of each unit of UCB to initial and sustained engraftment ...


Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma

OBJECTIVES: Primary - To systematically analyze the phenotype and molecular characteristics in patients with primary mediastinal diffuse large B-cell lymphoma. - To determine the PET response rate following chemoimmunotherapy in these patients. Secondary - To obtain data, on a nonrandomized basis, regarding the outcomes of treatment using different chemoimmunotherapy regimens ...

Phase N/A

Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia

OBJECTIVES: - To test in a randomized way the type and intensity of reintensification therapy for pediatric patients with acute lymphoblastic leukemia in each risk group: standard-risk (SR), intermediate-risk (IR), and high-risk (HR) group. - To compare two shorter elements of reintensification (protocol III x 2 courses) to one (protocol ...


Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

OBJECTIVES: Primary - To identify novel biomarkers of disease that would help in the initial diagnosis of myelodysplastic syndromes (MDS). Secondary - To understand the genesis of anemia in cancers. - To identify novel biomarkers of disease that predict progression of MDS to acute myeloid leukemia. OUTLINE: Blood and bone ...

Phase N/A

Epidermal Growth Factor Receptor Mutations in the Blood of Patients With Advanced Non-Small Cell Lung Cancer

OBJECTIVES: - Determine if epidermal growth factor receptor (EGFR) mutation exists in the peripheral blood of patients with advanced non-small cell lung cancer (NSCLC). - Estimate the frequency of EGFR mutation in these patients. - Correlate the presence of EGFR mutation in blood with EGFR mutation in primary or metastatic ...

Phase N/A

Anti-CD45 Monoclonal Antibody Cytarabine Cyclophosphamide and Total-Body Irradiation With or Without Alemtuzumab in Treating Patients Undergoing a Donor Stem Cell Transplant For Advanced Leukemia or Other Hematologic Cancer

OBJECTIVES: Primary - To evaluate the toxicity and the anti-tumor activity of anti-CD45 monoclonal antibody in patients with relapsed or resistant leukemia or other hematologic malignancy undergoing allogeneic stem cell transplantation. Secondary - To describe the effects of anti-CD45 on normal hematopoiesis and on complement levels. - To describe the ...