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Blood Cancer Clinical Trials

A listing of Blood Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (746) clinical trials

Study of Tumor and Blood Samples From Women With Breast Cancer

OBJECTIVES: Primary - Assess relapse locally or remotely using biomarkers collected from primary tumor and blood samples from women with breast cancer during the first 2 years after diagnosis. Secondary - Evaluate all relapses. - Assess survival without relapse. - Determine correlation between biomarkers and relapse. OUTLINE: Primary tumor and ...

Phase N/A

Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial

OBJECTIVES: - To provide a mechanism for sample collection and submission for diagnostic review to determine eligibility of patients with suspected leukemia or related hematologic disorders for enrollment on ECOG leukemia clinical trials. - To obtain baseline samples for correlative studies outlined in parent clinical trials. OUTLINE: This is a ...

Phase N/A

Studying Blood Samples in Young Patients With Cytopenia After a Donor Stem Cell Transplant

OBJECTIVES: Primary - To study hematopoietic chimerism in whole blood and different cell populations (i.e., CD14, CD15, CD 56, CD3, and CD19) as well as in dendritic cells and regulatory T cells after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in patients with refractory cytopenia. - To compare ...

Phase N/A

Collecting Samples From Patients With Primary Systemic Amyloidosis

OBJECTIVES: - To establish and maintain a database of clinical material (i.e., blood, urine, and tissue) and information on patients with primary systemic amyloidosis. OUTLINE: Blood, urine, tissue, and bone marrow samples are collected during standard laboratory evaluations to maintain a repository of biospecimens in the Gerry Amyloid Research Laboratory, ...

Phase N/A

Collecting Stem Cells in Patients With Waldenstrom's Macroglobulinemia

OBJECTIVES: - Harvest and store adequate CD34+ stem cells from patients with Waldenstrom's macroglobulinemia (WM) for potential future use in transplantation strategies. - Evaluate the ability to harvest stem cells after therapy for WM (e.g., fludarabine-based chemotherapy) by evaluating the number of days to adequate harvest. - Collect aliquots of ...

Phase N/A

Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

OBJECTIVES: - To collect biological specimens from patients with osteosarcoma at Children's Oncology Group (COG) institutions. - To provide a repository for long-term storage of osteosarcoma-related biological materials. - To make these specimens available to qualified researchers to understand the biology of osteosarcoma and correlate these results with the patients' ...

Phase N/A

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

OBJECTIVES: Primary - To identify novel biomarkers of disease that would help in the initial diagnosis of myelodysplastic syndromes (MDS). Secondary - To understand the genesis of anemia in cancers. - To identify novel biomarkers of disease that predict progression of MDS to acute myeloid leukemia. OUTLINE: Blood and bone ...

Phase N/A

Studying Tumor Tissue Samples and Blood Samples to Learn More About DNA Changes in Patients With Lung Cancer

OBJECTIVES: - Examine the mutational status of the EGFR pathway in tumor and blood samples from patients with lung cancer. - Correlate the EGFR pathway mutations in these samples with clinical outcomes of these patients. OUTLINE: Archived tumor tissue and blood samples are analyzed via PCR to detect EGFR pathway ...

Phase N/A

Effects of Monoclonal Antibody GC1008 in Blood Samples From Patients With Unresectable Locally Advanced or Metastatic Kidney Cancer or Malignant Melanoma Treated on Clinical Trial NCI-06-C-0200

OBJECTIVES: - To determine whether treatment with human anti-TGF-beta monoclonal antibody GC1008 results in a detectable decrease in phospho-Smad2 levels in freshly collected blood samples from patients with unresectable locally advanced or metastatic renal cell carcinoma or malignant melanoma treated on clinical trial NCI-06-C-0200. - To determine whether the decrease ...

Phase N/A

Epidermal Growth Factor Receptor Mutations in the Blood of Patients With Advanced Non-Small Cell Lung Cancer

OBJECTIVES: - Determine if epidermal growth factor receptor (EGFR) mutation exists in the peripheral blood of patients with advanced non-small cell lung cancer (NSCLC). - Estimate the frequency of EGFR mutation in these patients. - Correlate the presence of EGFR mutation in blood with EGFR mutation in primary or metastatic ...

Phase N/A